P2C45_ARATH
ID P2C45_ARATH Reviewed; 245 AA.
AC Q3EAZ3; Q9LI90;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Putative protein phosphatase 2C-like protein 45;
DE Short=AtPP2C45;
DE AltName: Full=Protein phosphatase AP2C6;
GN OrderedLocusNames=At3g27140; ORFNames=MYF5.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19021904; DOI=10.1186/1471-2164-9-550;
RA Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.;
RT "Genome-wide and expression analysis of protein phosphatase 2C in rice and
RT Arabidopsis.";
RL BMC Genomics 9:550-550(2008).
CC -!- SIMILARITY: Belongs to the PP2C family. {ECO:0000305}.
CC -!- CAUTION: Although related to the protein phosphatase 2C family, lacks
CC some of the conserved residues that bind manganese, suggesting it has
CC no phosphatase activity. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB01931.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP001312; BAB01931.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77272.1; -; Genomic_DNA.
DR RefSeq; NP_189350.2; NM_113628.2.
DR AlphaFoldDB; Q3EAZ3; -.
DR SMR; Q3EAZ3; -.
DR STRING; 3702.AT3G27140.1; -.
DR PaxDb; Q3EAZ3; -.
DR PRIDE; Q3EAZ3; -.
DR ProteomicsDB; 248715; -.
DR EnsemblPlants; AT3G27140.1; AT3G27140.1; AT3G27140.
DR GeneID; 822333; -.
DR Gramene; AT3G27140.1; AT3G27140.1; AT3G27140.
DR KEGG; ath:AT3G27140; -.
DR Araport; AT3G27140; -.
DR TAIR; locus:2095133; AT3G27140.
DR eggNOG; KOG0698; Eukaryota.
DR HOGENOM; CLU_013173_10_0_1; -.
DR InParanoid; Q3EAZ3; -.
DR OMA; MRRWHDE; -.
DR OrthoDB; 1044139at2759; -.
DR PhylomeDB; Q3EAZ3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q3EAZ3; baseline.
DR Genevisible; Q3EAZ3; AT.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0006470; P:protein dephosphorylation; IBA:GO_Central.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; -; 2.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase_dom.
DR PANTHER; PTHR13832; PTHR13832; 2.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; SSF81606; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..245
FT /note="Putative protein phosphatase 2C-like protein 45"
FT /id="PRO_0000367969"
FT DOMAIN 1..188
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01082"
SQ SEQUENCE 245 AA; 26567 MW; 433993D550B837E0 CRC64;
MEDRFSTITN LHGDRKQAIF GVYVGHGGVK AAECPAKNLD KNIVEEVVGK RHELEIAEAG
GSSCVTALVS EGSLVVSNAG DCRAVMSVGG VAKGSLVVPR GIGDAQLKKW VIAEPETKIS
RVEHDHEFLI LASHGLWDKV SNQEAVDIAR PFCLRTEKPL LLAACKKLVD LSASRGSFDD
ISVMLIPLRP VRIEKRGILE DVSSSKANSI ARDIAISVTR DGRFRSYLAR GGPGWLLSRI
EEDKR