位置:首页 > 蛋白库 > A30BL_HUMAN
A30BL_HUMAN
ID   A30BL_HUMAN             Reviewed;         258 AA.
AC   A7E2S9; B8ZZL7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 3.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Putative ankyrin repeat domain-containing protein 30B-like;
GN   Name=ANKRD30BL; Synonyms=NCRNA00164;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 42-258 (ISOFORM 2).
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=A7E2S9-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=A7E2S9-2; Sequence=VSP_039808;
CC   -!- MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC097532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC098826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471058; EAX11682.1; -; Genomic_DNA.
DR   EMBL; BC150521; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS86883.1; -. [A7E2S9-1]
DR   AlphaFoldDB; A7E2S9; -.
DR   SMR; A7E2S9; -.
DR   STRING; 9606.ENSP00000386398; -.
DR   BioMuta; ANKRD30BL; -.
DR   MassIVE; A7E2S9; -.
DR   PaxDb; A7E2S9; -.
DR   PeptideAtlas; A7E2S9; -.
DR   PRIDE; A7E2S9; -.
DR   Ensembl; ENST00000295181.6; ENSP00000295181.6; ENSG00000163046.16. [A7E2S9-2]
DR   Ensembl; ENST00000409867.6; ENSP00000386398.1; ENSG00000163046.16. [A7E2S9-1]
DR   MANE-Select; ENST00000409867.6; ENSP00000386398.1; NM_001358416.1; NP_001345345.1.
DR   UCSC; uc061nxe.1; human. [A7E2S9-1]
DR   GeneCards; ANKRD30BL; -.
DR   HGNC; HGNC:35167; ANKRD30BL.
DR   HPA; ENSG00000163046; Tissue enriched (testis).
DR   neXtProt; NX_A7E2S9; -.
DR   OpenTargets; ENSG00000163046; -.
DR   VEuPathDB; HostDB:ENSG00000163046; -.
DR   eggNOG; KOG0504; Eukaryota.
DR   GeneTree; ENSGT00940000164163; -.
DR   HOGENOM; CLU_000134_9_4_1; -.
DR   InParanoid; A7E2S9; -.
DR   OMA; ACFNGHA; -.
DR   PhylomeDB; A7E2S9; -.
DR   TreeFam; TF337879; -.
DR   ChiTaRS; ANKRD30BL; human.
DR   Pharos; A7E2S9; Tdark.
DR   PRO; PR:A7E2S9; -.
DR   Proteomes; UP000005640; Chromosome 2.
DR   RNAct; A7E2S9; protein.
DR   Bgee; ENSG00000163046; Expressed in colonic epithelium and 81 other tissues.
DR   Genevisible; A7E2S9; HS.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   Pfam; PF12796; Ank_2; 2.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 3.
PE   2: Evidence at transcript level;
KW   Alternative splicing; ANK repeat; Reference proteome; Repeat.
FT   CHAIN           1..258
FT                   /note="Putative ankyrin repeat domain-containing protein
FT                   30B-like"
FT                   /id="PRO_0000341256"
FT   REPEAT          71..100
FT                   /note="ANK 1"
FT   REPEAT          104..133
FT                   /note="ANK 2"
FT   REPEAT          137..166
FT                   /note="ANK 3"
FT   REPEAT          170..199
FT                   /note="ANK 4"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..258
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        216..231
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         206..258
FT                   /note="VHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLAERTPDTAESLVERTPD
FT                   E -> TALMLAICHGSSEIVGKLLQQNVDICAEATCGMIAERYAVACGFNL (in
FT                   isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:15489334"
FT                   /id="VSP_039808"
SQ   SEQUENCE   258 AA;  28549 MW;  529F3DEEC99F27E1 CRC64;
     MERLSAAPVK GQTGPERPSP FSQLVYTNND SYVIHHGDLR KIHKAASRGQ AWKLERMMKK
     TTMDLNIRDA KKRTALYWAC ANGHAEVVTL LVDRKCQLDV LDGENRTILM KALQCQREAC
     ANILIDSGAD PNIVDVYGNT AVHYAVNSEN LSVVAKLLSC GADIEVKNKA GHTPLLLAIR
     KRSEEIVEFL LTKNANANAV DKFKCVHQQL LEYKQKISKN SQNSNPEGTS EGTPDEAAPL
     AERTPDTAES LVERTPDE
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024