P30_ASFE7
ID P30_ASFE7 Reviewed; 194 AA.
AC P29999;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1993, sequence version 1.
DT 23-FEB-2022, entry version 55.
DE RecName: Full=Phosphoprotein p30;
DE AltName: Full=p32;
OS African swine fever virus (isolate Pig/Spain/E-75/1975) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=686262;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBCELLULAR LOCATION.
RX PubMed=1604821; DOI=10.1016/0042-6822(92)90718-5;
RA Afonso C.L., Alcaraz C., Brun A., Sussman M.D., Onisk D.V., Escribano J.M.,
RA Rock D.L.;
RT "Characterization of p30, a highly antigenic membrane and secreted protein
RT of African swine fever virus.";
RL Virology 189:368-373(1992).
CC -!- FUNCTION: Modifies the subcellular distribution of heterogeneous
CC nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate
CC HNRNPK functions related to processing and export of mRNAs during ASFV
CC infection (By similarity). Necessary for virus internalization (By
CC similarity). {ECO:0000250|UniProtKB:P34204}.
CC -!- SUBUNIT: Oligomer. Interacts with host HNRNPK.
CC {ECO:0000250|UniProtKB:P34204}.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250|UniProtKB:P34204}.
CC Host nucleus {ECO:0000250|UniProtKB:P34204}. Virion
CC {ECO:0000250|UniProtKB:P34204}.
CC -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC {ECO:0000305}.
CC -!- PTM: Phosphorylated on serine residues in the 115 N-terminal amino
CC acids. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the asfivirus phosphoprotein p30 family.
CC {ECO:0000305}.
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DR EMBL; M88336; AAA42729.1; -; Genomic_DNA.
DR PIR; A40237; WMXF30.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Early protein; Host cytoplasm; Host nucleus; Host-virus interaction;
KW Phosphoprotein; Virion.
FT CHAIN 1..194
FT /note="Phosphoprotein p30"
FT /id="PRO_0000221959"
SQ SEQUENCE 194 AA; 22348 MW; C11B2B11C70781C0 CRC64;
MDFILNISMK MEVIFKTDLR SSSQVVFHAG SLYNWFSVEI INSGRIVTTA IKTLLSTVKY
DIVKSAHIYA GQGYTEHQAQ EEWNMILHVL FEEETESSAS SESIHEKNDN ETNECTSSFE
TLFEQEPSSE EPKDSKLYML AQKTVQHIEQ YGKAPDFNKV IRAHNFIQTI HGTPLKEEEK
EVVRLMVIKL LKKK