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P30_ASFE7
ID   P30_ASFE7               Reviewed;         194 AA.
AC   P29999;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   23-FEB-2022, entry version 55.
DE   RecName: Full=Phosphoprotein p30;
DE   AltName: Full=p32;
OS   African swine fever virus (isolate Pig/Spain/E-75/1975) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=686262;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBCELLULAR LOCATION.
RX   PubMed=1604821; DOI=10.1016/0042-6822(92)90718-5;
RA   Afonso C.L., Alcaraz C., Brun A., Sussman M.D., Onisk D.V., Escribano J.M.,
RA   Rock D.L.;
RT   "Characterization of p30, a highly antigenic membrane and secreted protein
RT   of African swine fever virus.";
RL   Virology 189:368-373(1992).
CC   -!- FUNCTION: Modifies the subcellular distribution of heterogeneous
CC       nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate
CC       HNRNPK functions related to processing and export of mRNAs during ASFV
CC       infection (By similarity). Necessary for virus internalization (By
CC       similarity). {ECO:0000250|UniProtKB:P34204}.
CC   -!- SUBUNIT: Oligomer. Interacts with host HNRNPK.
CC       {ECO:0000250|UniProtKB:P34204}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250|UniProtKB:P34204}.
CC       Host nucleus {ECO:0000250|UniProtKB:P34204}. Virion
CC       {ECO:0000250|UniProtKB:P34204}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- PTM: Phosphorylated on serine residues in the 115 N-terminal amino
CC       acids. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the asfivirus phosphoprotein p30 family.
CC       {ECO:0000305}.
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DR   EMBL; M88336; AAA42729.1; -; Genomic_DNA.
DR   PIR; A40237; WMXF30.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Early protein; Host cytoplasm; Host nucleus; Host-virus interaction;
KW   Phosphoprotein; Virion.
FT   CHAIN           1..194
FT                   /note="Phosphoprotein p30"
FT                   /id="PRO_0000221959"
SQ   SEQUENCE   194 AA;  22348 MW;  C11B2B11C70781C0 CRC64;
     MDFILNISMK MEVIFKTDLR SSSQVVFHAG SLYNWFSVEI INSGRIVTTA IKTLLSTVKY
     DIVKSAHIYA GQGYTEHQAQ EEWNMILHVL FEEETESSAS SESIHEKNDN ETNECTSSFE
     TLFEQEPSSE EPKDSKLYML AQKTVQHIEQ YGKAPDFNKV IRAHNFIQTI HGTPLKEEEK
     EVVRLMVIKL LKKK
 
 
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