P320_TRYBB
ID P320_TRYBB Reviewed; 290 AA.
AC P21787;
DT 01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1991, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Microtubule-associated protein P320;
DE Flags: Fragment;
OS Trypanosoma brucei brucei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=5702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3393912; DOI=10.1126/science.3393912;
RA Schneider A., Hemphill A., Wyler T., Seebeck T.;
RT "Large microtubule-associated protein of T. brucei has tandemly repeated,
RT near-identical sequences.";
RL Science 241:459-462(1988).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
CC -!- DOMAIN: Made of tandem repeats of a 38 amino acid segment.
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DR EMBL; M20569; AAA30211.1; -; Genomic_DNA.
DR AlphaFoldDB; P21787; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR InterPro; IPR040270; Microtub-assoc_Trypanosoma.
DR PANTHER; PTHR37448; PTHR37448; 1.
PE 4: Predicted;
KW Cytoplasm; Cytoskeleton; Microtubule; Repeat.
FT CHAIN <1..>290
FT /note="Microtubule-associated protein P320"
FT /id="PRO_0000058131"
FT REPEAT 1..38
FT REPEAT 39..76
FT REPEAT 77..114
FT REPEAT 115..152
FT REPEAT 153..190
FT REPEAT 191..228
FT REPEAT 229..266
FT REPEAT 267..>290
FT REGION 251..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT NON_TER 290
SQ SEQUENCE 290 AA; 34297 MW; 46C5C5F7DE23BA88 CRC64;
SEYRQKRTVG EEVTTDMRHV DESHFLTTTH EAYKPIDPSE YRQKRTVGEE VTTDMRHVDE
SHFLTTTHEA YKPIDPSEYR QKRTVGEEVT TDMRHVDESH FLTTTHEAYK PIDPSEYRQK
RTVGEEVTTD MRHVDESHFL TTTHEAYKPI DPSEYRQKRT VGEEVTTNMR HVDESHFLTT
THEAYKPIDP SEYRQKRTVG EEVTTDMRHV DESHFLTTTH EAYKPIDPSE YRQKRTVGEE
VTTDMRHVDE SHFLTTTHEA YKPIDPSEYR QKRTVGEEVT TDMRHVDESH