P37_MESHY
ID P37_MESHY Reviewed; 403 AA.
AC P15363;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=High affinity transport system protein p37;
DE Flags: Precursor;
GN Name=p37;
OS Mesomycoplasma hyorhinis (Mycoplasma hyorhinis).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mesomycoplasma.
OX NCBI_TaxID=2100;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 24-50.
RX PubMed=3208756; DOI=10.1002/j.1460-2075.1988.tb03283.x;
RA Dudler R., Schmidhauser C., Parish R.W., Wettenhall R.E.H., Schmidt T.;
RT "A mycoplasma high-affinity transport system and the in vitro invasiveness
RT of mouse sarcoma cells.";
RL EMBO J. 7:3963-3970(1988).
CC -!- FUNCTION: P37 is part of a high-affinity transport system.
CC -!- INTERACTION:
CC P15363; P07355: ANXA2; Xeno; NbExp=24; IntAct=EBI-12740262, EBI-352622;
CC -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor.
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DR EMBL; X14140; CAA32357.1; -; Genomic_DNA.
DR EMBL; M37339; AAA25427.1; -; Genomic_DNA.
DR PIR; S01828; S01828.
DR PDB; 3E78; X-ray; 1.90 A; A=1-403.
DR PDB; 3E79; X-ray; 1.90 A; A=1-403.
DR PDB; 3EKI; X-ray; 1.60 A; A=1-403.
DR PDBsum; 3E78; -.
DR PDBsum; 3E79; -.
DR PDBsum; 3EKI; -.
DR AlphaFoldDB; P15363; -.
DR SMR; P15363; -.
DR IntAct; P15363; 2.
DR EvolutionaryTrace; P15363; -.
DR GO; GO:0030430; C:host cell cytoplasm; IDA:AgBase.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030334; P:regulation of cell migration; IDA:AgBase.
DR GO; GO:0001932; P:regulation of protein phosphorylation; IDA:AgBase.
DR Gene3D; 3.40.190.180; -; 1.
DR Gene3D; 3.40.190.190; -; 1.
DR InterPro; IPR010592; CypI.
DR InterPro; IPR043099; CypI_dom_I.
DR InterPro; IPR043100; CypI_dom_II.
DR Pfam; PF06646; Mycoplasma_p37; 1.
DR PIRSF; PIRSF004523; Mycoplasma_p37; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell membrane; Direct protein sequencing; Lipoprotein;
KW Membrane; Palmitate; Signal; Transport.
FT SIGNAL 1..23
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303,
FT ECO:0000269|PubMed:3208756"
FT CHAIN 24..403
FT /note="High affinity transport system protein p37"
FT /id="PRO_0000018095"
FT LIPID 24
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 24
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
FT STRAND 44..51
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 52..55
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 59..62
FT /evidence="ECO:0007829|PDB:3E79"
FT HELIX 64..85
FT /evidence="ECO:0007829|PDB:3EKI"
FT TURN 88..92
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 97..104
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 106..114
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 122..125
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 127..136
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 140..152
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 170..182
FT /evidence="ECO:0007829|PDB:3EKI"
FT TURN 183..186
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 187..189
FT /evidence="ECO:0007829|PDB:3EKI"
FT TURN 192..196
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 203..205
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 206..213
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 217..223
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 225..236
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 240..245
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 248..250
FT /evidence="ECO:0007829|PDB:3EKI"
FT TURN 256..259
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 260..269
FT /evidence="ECO:0007829|PDB:3EKI"
FT TURN 270..272
FT /evidence="ECO:0007829|PDB:3E78"
FT HELIX 277..283
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 285..287
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 288..290
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 293..298
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 304..308
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 311..314
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 331..337
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 345..349
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 354..369
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 376..379
FT /evidence="ECO:0007829|PDB:3EKI"
FT STRAND 383..386
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 390..393
FT /evidence="ECO:0007829|PDB:3EKI"
FT HELIX 395..402
FT /evidence="ECO:0007829|PDB:3EKI"
SQ SEQUENCE 403 AA; 46118 MW; F924180309DBFFDF CRC64;
MLKKLKNFIL FSSIFSPIAF AISCSNTGVV KQEDVSVSQG QWDKSITFGV SEAWLNKKKG
GEKVNKEVIN TFLENFKKEF NKLKNANDKT KNFDDVDFKV TPIQDFTVLL NNLSTDNPEL
DFGINASGKL VEFLKNNPGI ITPALETTTN SFVFDKEKDK FYVDGTDSDP LVKIAKEINK
IFVETPYASW TDENHKWNGN VYQSVYDPTV QANFYRGMIW IKGNDETLAK IKKAWNDKDW
NTFRNFGILH GKDNSFSKFK LEETILKNHF QNKFTTLNED RSAHPNAYKQ KSADTLGTLD
DFHIAFSEEG SFAWTHNKSA TKPFETKANE KMEALIVTNP IPYDVGVFRK SVNQLEQNLI
VQTFINLAKN KQDTYGPLLG YNGYKKIDNF QKEIVEVYEK AIK
