P3_RDVA
ID P3_RDVA Reviewed; 1019 AA.
AC P22472;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1991, sequence version 1.
DT 02-JUN-2021, entry version 81.
DE RecName: Full=Outer capsid protein P3;
DE AltName: Full=Core protein P3;
OS Rice dwarf virus (isolate Akita) (RDV).
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Reoviridae; Sedoreovirinae; Phytoreovirus.
OX NCBI_TaxID=142803;
OH NCBI_TaxID=114194; Alopecurus aequalis.
OH NCBI_TaxID=90397; Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli).
OH NCBI_TaxID=94400; Nephotettix cincticeps (Green rice leafhopper) (Selenocephalus cincticeps).
OH NCBI_TaxID=4530; Oryza sativa (Rice).
OH NCBI_TaxID=147271; Paspalum.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA], AND PROTEIN SEQUENCE OF 501-519.
RX PubMed=2219733; DOI=10.1016/0042-6822(90)90314-h;
RA Suzuki N., Watanabe Y., Kusano T., Kitagawa Y.;
RT "Sequence analysis of the rice dwarf phytoreovirus segment S3 transcript
RT encoding for the major structural core protein of 114 kDa.";
RL Virology 179:455-459(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2243784; DOI=10.1093/nar/18.21.6419;
RA Yamada N., Uyeda I., Kudo H., Shikata E.;
RT "Nucleotide sequence of rice dwarf virus genome segment 3.";
RL Nucleic Acids Res. 18:6419-6419(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2251136; DOI=10.1093/nar/18.22.6700;
RA Kano H., Koizumi M., Noda H., Mizuno H., Tsukihara T., Ishikawa K.,
RA Hibino H., Omura T.;
RT "Nucleotide sequence of rice dwarf virus (RDV) genome segment S3 coding for
RT 114 K major core protein.";
RL Nucleic Acids Res. 18:6700-6700(1990).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS), AND FUNCTION.
RX PubMed=14527391; DOI=10.1016/j.str.2003.08.012;
RA Nakagawa A., Miyazaki N., Taka J., Naitow H., Ogawa A., Fujimoto Z.,
RA Mizuno H., Higashi T., Watanabe Y., Omura T., Cheng R.H., Tsukihara T.;
RT "The atomic structure of rice dwarf virus reveals the self-assembly
RT mechanism of component proteins.";
RL Structure 11:1227-1238(2003).
CC -!- FUNCTION: Capsid protein which self-assembles to form the inner
CC icosahedral capsid with a T=2 symmetry, and consisting of 60 P3 dimers.
CC {ECO:0000269|PubMed:14527391}.
CC -!- SUBUNIT: Homodimer. Homomultimer.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host cytoplasm
CC {ECO:0000250}. Note=Found in the interior of spherical cytoplasmic
CC structures, called virus factories, that appear early after infection
CC and are the site of viral replication and packaging. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phytoreovirus inner capsid protein P3
CC family. {ECO:0000305}.
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DR EMBL; X54620; CAA38440.1; -; Genomic_RNA.
DR EMBL; D00607; BAA00482.1; -; Genomic_RNA.
DR EMBL; D00693; BAA00597.1; -; Genomic_RNA.
DR PIR; A45341; A45341.
DR PDB; 1UF2; X-ray; 3.50 A; A/B=1-1019.
DR PDBsum; 1UF2; -.
DR SMR; P22472; -.
DR EvolutionaryTrace; P22472; -.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR InterPro; IPR016029; Inner_layer_core_VP3_Reovir.
DR InterPro; IPR015312; Innr_layr_core_VP3_Phytoreovir.
DR Pfam; PF09231; RDV-p3; 1.
DR SUPFAM; SSF56831; SSF56831; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Capsid protein; Direct protein sequencing; Host cytoplasm;
KW Outer capsid protein; Virion.
FT CHAIN 1..1019
FT /note="Outer capsid protein P3"
FT /id="PRO_0000222782"
FT CONFLICT 183..184
FT /note="QR -> HG (in Ref. 3; BAA00597)"
FT /evidence="ECO:0000305"
FT CONFLICT 304
FT /note="A -> S (in Ref. 2; BAA00482)"
FT /evidence="ECO:0000305"
FT HELIX 16..18
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 19..22
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 23..25
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 32..49
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 61..64
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 65..67
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 72..79
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 82..84
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 90..97
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 103..106
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 112..114
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 116..132
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 133..135
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 136..140
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 143..148
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 151..156
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 158..160
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 162..164
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 166..170
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 173..175
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 176..189
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 190..194
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 208..210
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 214..216
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 217..224
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 226..242
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 246..255
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 261..263
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 265..272
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 278..281
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 290..295
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 297..310
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 313..317
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 320..331
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 340..344
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 350..362
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 363..365
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 369..375
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 381..383
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 385..394
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 395..397
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 400..402
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 405..422
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 426..434
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 444..446
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 454..460
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 467..476
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 477..479
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 482..485
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 488..490
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 492..494
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 503..505
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 506..508
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 515..517
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 522..524
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 525..531
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 546..548
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 553..564
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 577..594
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 595..598
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 599..606
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 609..613
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 614..617
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 628..630
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 631..636
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 638..640
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 641..647
FT /evidence="ECO:0007829|PDB:1UF2"
FT TURN 663..666
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 667..686
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 690..693
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 696..711
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 717..720
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 722..726
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 732..740
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 749..767
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 768..771
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 772..776
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 778..782
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 793..800
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 803..805
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 806..812
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 815..822
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 825..827
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 829..831
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 833..835
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 836..842
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 849..853
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 867..872
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 876..885
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 900..909
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 919..928
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 942..949
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 950..952
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 956..958
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 961..963
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 967..971
FT /evidence="ECO:0007829|PDB:1UF2"
FT HELIX 972..978
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 981..988
FT /evidence="ECO:0007829|PDB:1UF2"
FT STRAND 1000..1002
FT /evidence="ECO:0007829|PDB:1UF2"
SQ SEQUENCE 1019 AA; 114291 MW; 5FE562F73E629C50 CRC64;
MDSTGRAYDG ASEFKSVLVT EGTSHYTPVE VYNILDELKT IKITSTIAEQ SVVSRTPIPL
SKIGLQDVKK LFDINVIKCG SSLRIVDEPQ VTFIVSYAKD IYDKFMCIEH DSAYEPSLTM
HRVRVIYSML NDYCAKMISE VPYESSFVGE LPVKSVTLNK LGDRNMDALA EHLLFEHDVV
NAQRENRIFY QRKSAPAVPV IFGDDLEPAV RERANLYHRY SVPYHQIELA LHALANDLLS
IQYCHPTVVY NYLSSRAPNF LRLDDQVSLK LTSAGIGTLM PRPVVQLLDY DLVYMSPLAL
NNLASRLLRK ISLHLVMQMV TAVQQDLGEV VSVSSNVTNP ASACLVRMNV QGVQTLAVFI
AQSMLNPNIS YGMISGLTLD CFSNFIYGAC LMLFQALIPP SALTARQRLD INNRFAYFLI
KCHATQATTA RLVANQVIYP VDAIDQWQSN GRDVLVAIYN NLLPGELVLT NLIQTYFRGN
TAQQAAEILI PADQTSYGAN ETRALSAPYL FGAPINMLAP DARLSTYKRD LALPDRSPIL
ITTVEGQNSI SIENLRHKTG LIRAMYLNGF VTQPPAWIRN ANSNTALLSR FLDATPNLLG
IYEAILANTY ANAVNVYCDS VYRADIPIEW KLHQSVDPQD LLFGVFGIVP QYQILNEAVP
DFFAGGEDIL ILQLIRAVYD TLSNKLGRNP ADIFHLEEVF KVIEEIVSVL VQQKIDVRKY
FTESMRSGSF SKPRWDNFLR RPVAQRLPNL YSVIMTQADH VYNYMTQLTH IIPITDCFYI
VKNSGFVDRG STGPVIASSS VYENVLKVVH TIADFDAANA LRLQRRRVDN TSYTDSLSDM
FNGLRSISSS EFVRSVNGRS VFTEGRIDAI KVNMRAKFDL QFITEEGGYS KPPNVKKLMF
SDFLSFLDSH KSDYRPPLLT VPITIGLNNL GETNSNTLRM RSEAIDEYFS SYVGAQILVP
INVVDTRVYT EFSELRNFFT GDVVIRDDPF DVWDGVKATY IPIGVHGVRL DPNGDQPPL
