ID   P43_XENBO               Reviewed;         365 AA.
AC   P25066;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=P43 5S RNA-binding protein;
DE   AltName: Full=42S P43;
DE   AltName: Full=Thesaurin-B;
OS   Xenopus borealis (Kenyan clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2331751; DOI=10.1016/0092-8674(90)90809-s;
RA   Joho K.E., Darby M.K., Crawford E.T., Brown D.D.;
RT   "A finger protein structurally similar to TFIIIA that binds exclusively to
RT   5S RNA in Xenopus.";
RL   Cell 61:293-300(1990).
CC   -!- FUNCTION: p43 is a 5S RNA binding protein which is a major constituent
CC       of oocytes and comprises part of a 42S ribonucleoprotein storage
CC       particle.
CC   -!- SUBUNIT: The 42S RNP particle comprises four subunits each of which
CC       contains one molecule of 5S RNA, three molecules of tRNA, two molecules
CC       of p50 (EF1-alpha) and one molecule of the 5S RNA binding protein 43.
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DR   EMBL; M32471; AAA49712.1; -; mRNA.
DR   PIR; A34895; A34895.
DR   AlphaFoldDB; P25066; -.
DR   SMR; P25066; -.
DR   PRIDE; P25066; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 4.
DR   SMART; SM00355; ZnF_C2H2; 9.
DR   SUPFAM; SSF57667; SSF57667; 4.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE   2: Evidence at transcript level;
KW   Metal-binding; Repeat; RNA-binding; Zinc; Zinc-finger.
FT   CHAIN           1..365
FT                   /note="P43 5S RNA-binding protein"
FT                   /id="PRO_0000047088"
FT   ZN_FING         15..39
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         45..69
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         75..100
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         106..130
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         136..160
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         163..187
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         191..213
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         220..245
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         251..275
FT                   /note="C2H2-type 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ   SEQUENCE   365 AA;  41727 MW;  D7E8C76E80E42EF2 CRC64;
     MQNVGPTEPS KSQVFRCPAA GCKAVYRKEG KLRDHMAGHS EQKLWKCGKK DCGKMFARKR
     QIQKHMKRHL TLKKHSCPTA GCKMTFSTKK SLSRHKLYKH GDAVPLKCSV PGCKRSFRKK
     RALRIHVSEH SNEPLSVCDV PGCGWKSTSA AKLAAHHRRH GGYRCSYEDC QTVSPTWTAL
     QTHLKKHPLE LQCAACKKPF KKASALRRHK ATHAKNPLQL PCPRQDCDKI FSTVFNLTHH
     LRKVHLCLQT HRCPHSNCTR SFAMRESLVR HLVVHDPERK KLKLKFGRRP SKFLGRGTRC
     PTPVVEEDLS HLFSRKLLFH YKTRLETNLS GLFNERQLRE PAEPEVNLSG LFQLPQGRPK
     AEKAA