ID   P43_XENLA               Reviewed;         365 AA.
AC   P25456;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=P43 5S RNA-binding protein;
DE   AltName: Full=42S P43;
DE   AltName: Full=Thesaurin-B;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2331751; DOI=10.1016/0092-8674(90)90809-s;
RA   Joho K.E., Darby M.K., Crawford E.T., Brown D.D.;
RT   "A finger protein structurally similar to TFIIIA that binds exclusively to
RT   5S RNA in Xenopus.";
RL   Cell 61:293-300(1990).
CC   -!- FUNCTION: p43 is a 5S RNA binding protein which is a major constituent
CC       of oocytes and comprises part of a 42S ribonucleoprotein storage
CC       particle.
CC   -!- SUBUNIT: The 42S RNP particle comprises four subunits each of which
CC       contains one molecule of 5S RNA, three molecules of tRNA, two molecules
CC       of p50 (EF1-alpha) and one molecule of the 5S RNA binding protein 43.
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DR   EMBL; M32473; AAA49714.1; -; mRNA.
DR   PIR; C34895; C34895.
DR   RefSeq; NP_001081272.1; NM_001087803.1.
DR   AlphaFoldDB; P25456; -.
DR   SMR; P25456; -.
DR   PRIDE; P25456; -.
DR   GeneID; 397745; -.
DR   KEGG; xla:397745; -.
DR   CTD; 397745; -.
DR   Xenbase; XB-GENE-6252610; 42sp43.L.
DR   OrthoDB; 1318335at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 397745; Expressed in oocyte and 6 other tissues.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 4.
DR   SMART; SM00355; ZnF_C2H2; 9.
DR   SUPFAM; SSF57667; SSF57667; 4.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE   2: Evidence at transcript level;
KW   Metal-binding; Reference proteome; Repeat; RNA-binding; Zinc; Zinc-finger.
FT   CHAIN           1..365
FT                   /note="P43 5S RNA-binding protein"
FT                   /id="PRO_0000047089"
FT   ZN_FING         15..39
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         45..69
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         75..100
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         106..130
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         136..160
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         163..187
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         191..213
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         220..245
FT                   /note="C2H2-type 8"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         251..275
FT                   /note="C2H2-type 9"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ   SEQUENCE   365 AA;  41694 MW;  2EB5BE66D7192995 CRC64;
     MKNVGETGPG KCQLLRCPAA GCKAFYRKEG KLQDHMAGHS EQKPWKCGIK DCDKVFARKR
     QILKHVKRHL ALKKLSCPTA GCKMTFSTKK SLSRHKLYKH GEAVPLKCFV PGCKRSFRKK
     RALRRHLSVH SNEPLSVCDV PGCSWKSSSV AKLVAHQKRH RGYRCSYEGC QTVSPTWTAL
     QTHVKKHPLE LQCAACKKPF KKASALRRHK ATHAKKPLQL PCPRQDCDKT FSSVFNLTHH
     VRKLHLCLQT HRCPHSGCTR SFAMRESLLR HLVVHDPERK KLKLKFVRGP SKFLGRGTRC
     RTPVVEEDLS HLFSRKLLFH FKTRLETNLS GLFNERQLRE PAEPEVNLSG LFQRPQGRAK
     AEKSA