ID   P46_MESH2               Reviewed;         416 AA.
AC   P0C0J7; P46192; Q600E4;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=46 kDa surface antigen;
DE   AltName: Full=p46;
DE   Flags: Precursor;
GN   Name=p46; OrderedLocusNames=mhp511;
OS   Mesomycoplasma hyopneumoniae (strain 232) (Mycoplasma hyopneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mesomycoplasma.
OX   NCBI_TaxID=295358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=232;
RX   PubMed=15489423; DOI=10.1128/jb.186.21.7123-7133.2004;
RA   Minion F.C., Lefkowitz E.J., Madsen M.L., Cleary B.J., Swartzell S.M.,
RA   Mahairas G.G.;
RT   "The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of
RT   swine mycoplasmosis.";
RL   J. Bacteriol. 186:7123-7133(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAV27597.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE017332; AAV27597.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; P0C0J7; -.
DR   SMR; P0C0J7; -.
DR   STRING; 295358.mhp511; -.
DR   PRIDE; P0C0J7; -.
DR   EnsemblBacteria; AAV27597; AAV27597; mhp511.
DR   KEGG; mhy:mhp511; -.
DR   eggNOG; COG4213; Bacteria.
DR   HOGENOM; CLU_612270_0_0_14; -.
DR   PhylomeDB; P0C0J7; -.
DR   Proteomes; UP000006822; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           28..416
FT                   /note="46 kDa surface antigen"
FT                   /id="PRO_0000018097"
FT   LIPID           28
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           28
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   416 AA;  45401 MW;  F4C5C82DCE704B53 CRC64;
     MLRKKFLYSS AIYATSLASI IAFVAAGCGQ TESGSTSDSK PQAETLKHKV SNDSIRIALT
     DPDNPRWISA QKDIISYVDE TEAATSTITK NQDAQNNWLT QQANLSPAPK GFIIAPENGS
     GVGTAVNTIA DKGIPIVAYD RLITGSDKYD WYVSFDNEKV GELQGLSLAA GLLGKEDGAF
     DSIDQMNEYL KSHMPQETIS FYTIAGSQDD NNSQYFYNGA MKVLKELMKN SQNKIIDLSP
     EGENAVYVPG WNYGTAGQRI QSFLTINKDP AGGNKIKAVG SKPASIFKGF LAPNDGMAEQ
     AITKLKLEGF DTQKIFVTGQ DYNDKAKTFI KDGDQNMTIY KPDKVLGKVA VEVLRVLIAK
     KNKASRSEVE NELKAKLPNI SFKYDNQTYK VQGKNINTIL VSPVIVTKAN VDNPDA