P48_NPVAC
ID P48_NPVAC Reviewed; 387 AA.
AC Q00732;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 2.
DT 23-FEB-2022, entry version 48.
DE RecName: Full=p48 protein;
DE AltName: Full=p45 protein;
GN Name=P48;
OS Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX NCBI_TaxID=46015;
OH NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C6;
RX PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT virus.";
RL Virology 202:586-605(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=HR3;
RA Lu A., Craig A., Carstens E.B.;
RL Submitted (JUN-1994) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-100.
RC STRAIN=HR3;
RX PubMed=1529529; DOI=10.1016/0042-6822(92)91206-a;
RA Lu A., Carstens E.B.;
RT "Nucleotide sequence and transcriptional analysis of the p80 gene of
RT Autographa californica nuclear polyhedrosis virus: a homologue of the
RT Orgyia pseudotsugata nuclear polyhedrosis virus capsid-associated gene.";
RL Virology 190:201-209(1992).
RN [4]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=18656219; DOI=10.1016/j.virol.2008.06.015;
RA Yuan M., Wu W., Liu C., Wang Y., Hu Z., Yang K., Pang Y.;
RT "A highly conserved baculovirus gene p48 (ac103) is essential for BV
RT production and ODV envelopment.";
RL Virology 379:87-96(2008).
CC -!- FUNCTION: Plays an essential role in the production of budded virions
CC (BVs) as well as in the envelopment of occluded derived virions (ODVs).
CC {ECO:0000269|PubMed:18656219}.
CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000269|PubMed:18656219}. Host
CC cytoplasm {ECO:0000269|PubMed:18656219}.
CC -!- SIMILARITY: Belongs to the baculoviridae p48 family. {ECO:0000305}.
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DR EMBL; L22858; AAA66733.1; -; Genomic_DNA.
DR EMBL; U10885; AAB08769.1; -; Genomic_DNA.
DR EMBL; M94914; AAA46731.1; -; Genomic_DNA.
DR PIR; H72862; H72862.
DR RefSeq; NP_054133.1; NC_001623.1.
DR SMR; Q00732; -.
DR GeneID; 1403936; -.
DR KEGG; vg:1403936; -.
DR Proteomes; UP000008292; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR006962; P48_Baculovir.
DR Pfam; PF04878; Baculo_p48; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host nucleus; Late protein; Reference proteome.
FT CHAIN 1..387
FT /note="p48 protein"
FT /id="PRO_0000132910"
SQ SEQUENCE 387 AA; 45313 MW; C22A586D56180E82 CRC64;
MCAYRLQYSL RFNIYDRFEN VCFEAQLLQD EIDSLCFLFS KYFNQSLIVD SKGLTFFTEF
NKCIVSIKSS FENQANNTDN IHNVKNIFSI FLRDEFIKQV PHFRTIMQYL QKYYNPTPAP
DVDAIMCQSC KPANKIQCFE CKCKYLASSL STLDAGLQNG WDIFLRPMFG MPLMLYVLLR
TDYKNESDII NENNLITQIF VQFFYNLICD KAYSLYTKRD MCVPFVKECK KATVGLRQED
HERVLSILSA QCNGCSTVAN GDRLLLPFKN FMIEMGRNTK MKKVNKIAST VLIGFYLRHY
LESLPNKAYP VAELELRNVC RFIMSKYSDE NINLLIHKLK LIKIDICNVL MTEMIVPETF
IRHIITKYQL DNEISLLIEL NHDCFNK