P49_ASFK5
ID P49_ASFK5 Reviewed; 438 AA.
AC P0C9Z6;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 23-FEB-2022, entry version 16.
DE RecName: Full=Minor capsid protein p49 {ECO:0000250|UniProtKB:Q65165};
DE Short=p49;
GN OrderedLocusNames=Ken-087;
OS African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=561445;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kutish G.F., Rock D.L.;
RT "African swine fever virus genomes.";
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with the penton and the other minor capsid proteins
CC (M1249L, p17), forms a complicated network immediately below the outer
CC capsid shell, stabilizing the whole capsid (By similarity). Plays an
CC essential role in the formation of infectious virus particles.
CC Especially required for the formation of the capsid vertices (By
CC similarity). During virion assembly, associates with the membrane and
CC probably mediates the docking of the penton complex to the inner
CC membrane, where it recruits the capsomers to form the penton core (By
CC similarity). {ECO:0000250|UniProtKB:Q65165}.
CC -!- SUBCELLULAR LOCATION: Virion. Note=Localizes in close proximity to the
CC capsid vertices. {ECO:0000250|UniProtKB:Q65165}.
CC -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the asfivirus p49 structural protein family.
CC {ECO:0000305}.
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DR EMBL; AY261360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PRIDE; P0C9Z6; -.
DR Proteomes; UP000000861; Genome.
PE 3: Inferred from homology;
KW Late protein; Virion.
FT CHAIN 1..438
FT /note="Minor capsid protein p49"
FT /id="PRO_0000373412"
SQ SEQUENCE 438 AA; 49358 MW; 3598F272B2CC281D CRC64;
MYHDYASKLL ADYRSDPPLW ESDLPRHNRY SDNILNARYC GNKNGAAPVY NECTNSPGKA
EKGLQLSDLR NFSFMLNPQH KNIGYGDAQD LEPYSPIPKD KLFNNLKIHR PAFSTHTENL
IRRNVVRTEK KTFPQVATLK STQKNCLTQP SSLPSLKNPK NISMPSTRFS EHIKFFSYED
VPKLRIKGTI KHEQHLGDQM PGQHYNGYIP HKDVYNILCL AHNLPASVEK VMAGRGIPLG
NPHVKPNIEQ ELIKSTCTYT GVPILGPLPS KDLQHGREYQ EFSANRHMLQ VSNILHSVFA
NHSIKPQILE DIPTLNAQLT SIKPVSPFLN KAYQTHYMEN IVTLVPRFKS IANYSSPIPH
YSKRNSGQAE YFDTSKQTIS RHNNYIPKYT GGIGDSKLDS SFPKDFNASS VPLTSAEKDH
SLRGDNSACC ISSISPSL