ID   P49_ASFM2               Reviewed;         437 AA.
AC   Q8V9T4; Q8V9T6;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 2.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Minor capsid protein p49 {ECO:0000250|UniProtKB:Q65165};
DE            Short=p49;
GN   OrderedLocusNames=Mal-083; ORFNames=L09JL, L09LL;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Roberts P.C., Lu Z., Rock D.L.;
RT   "Nucleotide sequence and analysis of 16.25 kilobase pairs of the African
RT   swine fever virus genome that span the central variable region.";
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Together with the penton and the other minor capsid proteins
CC       (M1249L, p17), forms a complicated network immediately below the outer
CC       capsid shell, stabilizing the whole capsid (By similarity). Plays an
CC       essential role in the formation of infectious virus particles.
CC       Especially required for the formation of the capsid vertices (By
CC       similarity). During virion assembly, associates with the membrane and
CC       probably mediates the docking of the penton complex to the inner
CC       membrane, where it recruits the capsomers to form the penton core (By
CC       similarity). {ECO:0000250|UniProtKB:Q65165}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q65165}.
CC       Note=Localizes in close proximity to the capsid vertices.
CC       {ECO:0000250|UniProtKB:Q65165}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus p49 structural protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL31327.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AAL31329.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; L00966; AAL31327.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; L00966; AAL31329.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; Q8V9T4; -.
DR   Proteomes; UP000000860; Genome.
PE   3: Inferred from homology;
KW   Late protein; Virion.
FT   CHAIN           1..437
FT                   /note="Minor capsid protein p49"
FT                   /id="PRO_0000373414"
SQ   SEQUENCE   437 AA;  49205 MW;  439D35C1C7CCE1CF CRC64;
     MYHDYASKLL ADYRSDPPLW ESDLPRHNRY SDNILNSRYC GNKNGAEPVY NESTNSPGKA
     ERGLQLSDLR NFSFMLNPQH KNIGYGDAQD LEPYSSIPKN KLFNNFKNHR PAFSTHTENL
     IRRNVVRTEK KTFPQVASLK STQKHCLTQP SSLPSLKNPK NISVPSARFS EHTKFFSYED
     LPKLKTKGAI KHEQHLGDQM SGQYYNGYIP HKDVYNILCL AHNLPASVEK VIAGRGIPLG
     NPHVKPNIEQ ELIKSACAYT GIPIGPLPSK DLQHGREYQE FSANRHMLQV SNILHSVFAN
     HSIKPQILED IPTLNAQLTS IKPISPFLNK AYQTHYMENI VTLVPRFKSI ANYSSPIPNY
     SKRDSGQAEY FDTSKQTISR HNNYIPKYTG GIGDSKLDTT FPKDFNASSV PLTSAEKDHS
     LRGDNSACCI SSISPSL