ID   P49_ASFWA               Reviewed;         438 AA.
AC   P0C9Z5;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 21.
DE   RecName: Full=Minor capsid protein p49 {ECO:0000250|UniProtKB:Q65165};
DE            Short=p49;
GN   OrderedLocusNames=War-085;
OS   African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=561444;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Together with the penton and the other minor capsid proteins
CC       (M1249L, p17), forms a complicated network immediately below the outer
CC       capsid shell, stabilizing the whole capsid (By similarity). Plays an
CC       essential role in the formation of infectious virus particles.
CC       Especially required for the formation of the capsid vertices (By
CC       similarity). During virion assembly, associates with the membrane and
CC       probably mediates the docking of the penton complex to the inner
CC       membrane, where it recruits the capsomers to form the penton core (By
CC       similarity). {ECO:0000250|UniProtKB:Q65165}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q65165}.
CC       Note=Localizes in close proximity to the capsid vertices.
CC       {ECO:0000250|UniProtKB:Q65165}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus p49 structural protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY261366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000858; Genome.
PE   3: Inferred from homology;
KW   Late protein; Virion.
FT   CHAIN           1..438
FT                   /note="Minor capsid protein p49"
FT                   /id="PRO_0000373411"
FT   REGION          134..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..167
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   438 AA;  49463 MW;  029A995F906690A2 CRC64;
     MYHDYASKLL ADYRSDPPLW ESDLPRHNRY SDNILNSRYC GNKNGAAPVY NEYTNSPGKA
     EKGLQLSDLR NFSFMLNPQH KNIGYGDAQD LEPYSSIPKN KLFNHFKNYR PAFSTHTENL
     IKRNVVRTEK KTFPQVSGLK DTQKNCLTQP SSLPSLKNPK NSSVPSTRFS EHTKFFSYED
     LPKLRTKGTI KHEQHLGDQM PGQYYNGYIP HQDVYNILCL AHKLPASVEK EIAGRGIPLG
     NPHVKPNIEQ ELIKSTSTYT GVPMLGPLPP KDSQHGREYQ EFSANRHMLQ VSNILHSVFA
     NHSIKPQILE DIPVLNAQLA SIKPVSPFLN KAYQTHYMEN IVTLVPRFKS IANYSSPIPN
     YSKRNNGQAE YFDTSKQTIS RHNNYIPKYT GGIGDSRLDS TFPKDFNASS VPLTSAEKDH
     SLRGDNSACC ISSISPSL