ID   P4A_FOWPN               Reviewed;         891 AA.
AC   Q9J559;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Major core protein 4a precursor;
DE            Short=p4a;
DE   AltName: Full=Virion core protein 4a precursor;
GN   OrderedLocusNames=FPV174;
OS   Fowlpox virus (strain NVSL) (FPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Avipoxvirus.
OX   NCBI_TaxID=928301;
OH   NCBI_TaxID=7742; Vertebrata.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10729156; DOI=10.1128/jvi.74.8.3815-3831.2000;
RA   Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.;
RT   "The genome of fowlpox virus.";
RL   J. Virol. 74:3815-3831(2000).
CC   -!- FUNCTION: Core protein 4a is the most abundant virion protein. Major
CC       component of the virion core that undergoes proteolytic processing
CC       during the immature virion (IV) to mature virion (MV) transition (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with P39/A4. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Probably localizes to
CC       the virion core wall. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the poxviridae protein P4a family.
CC       {ECO:0000305}.
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DR   EMBL; AF198100; AAF44518.1; -; Genomic_DNA.
DR   RefSeq; NP_039137.1; NC_002188.1.
DR   PRIDE; Q9J559; -.
DR   GeneID; 1486722; -.
DR   KEGG; vg:1486722; -.
DR   Proteomes; UP000008597; Genome.
DR   GO; GO:0044423; C:virion component; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR005058; Poxvirus_P4A.
DR   Pfam; PF03395; Pox_P4A; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Virion.
FT   CHAIN           1..891
FT                   /note="Major core protein 4a precursor"
FT                   /id="PRO_0000099217"
SQ   SEQUENCE   891 AA;  102269 MW;  21D64EE473D74B72 CRC64;
     MMLIKNIVTL DQLESSDYLY KLISSVLPSL CLDYKIDPKL ANGYVHALDT IYSPELISIL
     TDGERSQQLD TLGINYILSR KNDLGIYFPI NIRENGEIVS TWNKNTGGYT NPIPCTISFN
     DLPPFTKILI QIRTMGCEAH ARYFGGYVEH PSSPNILSPK INPNISFANS YIHSLTYPYI
     EGRADYSTYR PLLINGIMEK KDLANLLNVR ALLEPMSRAI FDAIFKIQFH CNANNIVLVQ
     NPNIDTDLIT MQTLKYLVMY FQHFSGFTLR DIYLGGVRIR VDNSMLASYV VSIYFSKEIK
     YIEDNKLFSL DYIDQFVFRP DNSNLNITVT AQQLGIRILN MTSNRPYIIN LLNIVSKSLV
     RHRNVPKEIS LFWDGMSYDE YKNMKFIDMM FLGTTCYLFA LYNKNGITYC SMLNDVLRAE
     ETPIRICVFP RILKGKTIPT LIREILENIN NISVRDFPKY DTHDVKHIGL SDAGFMLFFQ
     FLRLMENKEP HIAVKEILMA YTGIKIDDKG SPYYITPESY RTFIFMLFKA MGFNVRVNRT
     TISSHSYTSY YVSPRVSKRY LTNMLQKASC SQSEAEKLLS SAHDLVSFML SVNNSSNRDS
     YRRINRSFFG GFKESASEED ATLVQFISPV NILDRINVKG ILSANALNEI MDTDVFLPEN
     ANFKENLKQL LKEDTIDGKS IAHIIPLNTI DRLIVSAGGV SVGELLENLD ERVPDENATN
     EVIELITNAL KDRNMKDSNF IATNILNSIT QISEKQMDGI KKITCHGTMM FKELAMHIYF
     TERYFKAKIS DDVKISILEK YRDFIELSKS LYKDLIGIDQ IKSVLSIVHR TGRNIDDNPI
     TQEDIQKAYN IARPKILKLT NYYTEMTKSY FENIKRIMNP EDANAVVFDN E