ID   P4R2A_DANRE             Reviewed;         420 AA.
AC   Q6P964; A7MBR6;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 2.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2-A;
GN   Name=ppp4r2a; Synonyms=ppp4r2; ORFNames=wu:fe11b04;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary, and Retina;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulatory subunit of serine/threonine-protein phosphatase 4
CC       (PP4C). {ECO:0000250}.
CC   -!- SUBUNIT: Serine/threonine-protein phosphatase 4 (PP4) occurs in
CC       different assemblies of the catalytic and one or more regulatory
CC       subunits. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PPP4R2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH60912.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAI51886.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC060912; AAH60912.1; ALT_INIT; mRNA.
DR   EMBL; BC151885; AAI51886.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q6P964; -.
DR   STRING; 7955.ENSDARP00000036492; -.
DR   PaxDb; Q6P964; -.
DR   ZFIN; ZDB-GENE-030131-4922; ppp4r2a.
DR   eggNOG; KOG3175; Eukaryota.
DR   InParanoid; Q6P964; -.
DR   PhylomeDB; Q6P964; -.
DR   Reactome; R-DRE-5693607; Processing of DNA double-strand break ends.
DR   PRO; PR:Q6P964; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0030289; C:protein phosphatase 4 complex; IBA:GO_Central.
DR   GO; GO:0019888; F:protein phosphatase regulator activity; IBA:GO_Central.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:GO_Central.
DR   InterPro; IPR015267; PPP4R2.
DR   PANTHER; PTHR16487; PTHR16487; 1.
DR   Pfam; PF09184; PPP4R2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..420
FT                   /note="Serine/threonine-protein phosphatase 4 regulatory
FT                   subunit 2-A"
FT                   /id="PRO_0000299370"
FT   REGION          157..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..199
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..221
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        222..251
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..268
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..296
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..342
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        343..360
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        361..410
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   420 AA;  46193 MW;  5CA1535C012B6FAB CRC64;
     MEIDTLLGAF RDFEKKGEKE SCPILDQFLS HVAKTGETMI QWSQFKSYFL FKLEKVMDDF
     KASCPEQRGP ANPNVEYIPF EEMKQRILKI VNGYNGIPFT IQRLCELLTE PKRNYAGTDK
     FLRGVEKNVM VVSCVYPTSE KKGSSCVNRM NGVMFPGNTS AFPDRNVNGP GTPRPLNRPK
     HSLSSNVATN GLPDSTESKE QASEQSERTV NESSASEAES HSGAVKSKHR DDEDATHAET
     HEAKRLKFDK EEEEEEDDEE EDEDGDEIKK ELDEPHSPCT SVAESSSDVP QSSTDVTAEV
     KDEDQEPSST QSEVVENGVD RSTSEDSPDP SHKATGSESD PKEQQAEEEE EEESAEAQET
     EETNDPVSSS SNNSSDEGVS SAETPSASPS SSTELPAEGS VTAEITSDNS ETADDNMEQD