ID   P538_METTH              Reviewed;         111 AA.
AC   O26638;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Protein MTH_538;
GN   OrderedLocusNames=MTH_538;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
RN   [2]
RP   STRUCTURE BY NMR, AND CHARACTERIZATION.
RX   PubMed=10964569; DOI=10.1006/jmbi.2000.4052;
RA   Cort J.R., Yee A., Edwards A.M., Arrowsmith C.H., Kennedy M.A.;
RT   "Structure-based functional classification of hypothetical protein MTH538
RT   from Methanobacterium thermoautotrophicum.";
RL   J. Mol. Biol. 302:189-203(2000).
CC   -!- FUNCTION: Not known. Could have a role in a phosphorylation-independent
CC       two-component response regulator system.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- SUBUNIT: Monomer. {ECO:0000305}.
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DR   EMBL; AE000666; AAB85044.1; -; Genomic_DNA.
DR   PIR; A69171; A69171.
DR   RefSeq; WP_010876177.1; NC_000916.1.
DR   PDB; 1EIW; NMR; -; A=2-111.
DR   PDBsum; 1EIW; -.
DR   AlphaFoldDB; O26638; -.
DR   BMRB; O26638; -.
DR   SMR; O26638; -.
DR   STRING; 187420.MTH_538; -.
DR   EnsemblBacteria; AAB85044; AAB85044; MTH_538.
DR   GeneID; 1470499; -.
DR   KEGG; mth:MTH_538; -.
DR   HOGENOM; CLU_140379_1_0_2; -.
DR   OMA; VGWNANC; -.
DR   EvolutionaryTrace; O26638; -.
DR   Proteomes; UP000005223; Chromosome.
DR   Gene3D; 3.40.50.9200; -; 1.
DR   InterPro; IPR036490; MTH538_sf.
DR   SUPFAM; SSF52206; SSF52206; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Magnesium; Reference proteome.
FT   CHAIN           1..111
FT                   /note="Protein MTH_538"
FT                   /id="PRO_0000138637"
FT   STRAND          5..9
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   HELIX           15..27
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   STRAND          31..33
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   STRAND          36..38
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   STRAND          40..45
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   HELIX           46..48
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   TURN            49..51
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   HELIX           53..63
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   TURN            64..67
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   STRAND          70..73
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   STRAND          76..79
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   HELIX           85..88
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   STRAND          90..93
FT                   /evidence="ECO:0007829|PDB:1EIW"
FT   HELIX           97..108
FT                   /evidence="ECO:0007829|PDB:1EIW"
SQ   SEQUENCE   111 AA;  12416 MW;  AFFEC3EB5F545CB8 CRC64;
     MTAEIRLYIT EGEVEDYRVF LERLEQSGLE WRPATPEDAD AVIVLAGLWG TRRDEILGAV
     DLARKSSKPI ITVRPYGLEN VPPELEAVSS EVVGWNPHCI RDALEDALDV I