ID   ASHWN_BOVIN             Reviewed;         232 AA.
AC   A2VDP0;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Ashwin;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Basal ganglia;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the tRNA-splicing ligase complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9BVC5}.
CC   -!- SIMILARITY: Belongs to the ashwin family. {ECO:0000305}.
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DR   EMBL; BC133333; AAI33334.1; -; mRNA.
DR   RefSeq; NP_001075008.1; NM_001081539.1.
DR   AlphaFoldDB; A2VDP0; -.
DR   SMR; A2VDP0; -.
DR   STRING; 9913.ENSBTAP00000016358; -.
DR   PaxDb; A2VDP0; -.
DR   PRIDE; A2VDP0; -.
DR   Ensembl; ENSBTAT00000016358; ENSBTAP00000016358; ENSBTAG00000012332.
DR   GeneID; 540024; -.
DR   KEGG; bta:540024; -.
DR   CTD; 114564110; -.
DR   VEuPathDB; HostDB:ENSBTAG00000012332; -.
DR   VGNC; VGNC:52615; C11H2orf49.
DR   eggNOG; ENOG502S0PQ; Eukaryota.
DR   GeneTree; ENSGT00390000007488; -.
DR   HOGENOM; CLU_104242_0_0_1; -.
DR   InParanoid; A2VDP0; -.
DR   OMA; SCNDQHR; -.
DR   OrthoDB; 1299864at2759; -.
DR   TreeFam; TF332084; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000012332; Expressed in oocyte and 106 other tissues.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0072669; C:tRNA-splicing ligase complex; ISS:UniProtKB.
DR   GO; GO:0048598; P:embryonic morphogenesis; IEA:InterPro.
DR   InterPro; IPR024887; Ashwin.
DR   PANTHER; PTHR28359; PTHR28359; 1.
DR   Pfam; PF15323; Ashwin; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..232
FT                   /note="Ashwin"
FT                   /id="PRO_0000284950"
FT   REGION          64..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..95
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..167
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        203..225
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         143
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BVC5"
FT   MOD_RES         182
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BVC5"
FT   MOD_RES         189
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BVC5"
FT   MOD_RES         193
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BVC5"
FT   MOD_RES         198
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BVC5"
SQ   SEQUENCE   232 AA;  25874 MW;  AED20BC73CF65D13 CRC64;
     MAGDVGGRSC TDSELLLHPE LLSQEFLLLT LEQKNITVEN DMRVNKDSLT DLYVQHAIPL
     PQRDLPKSRW GKMMEKKREQ HEIKKETKRS SPADGLRKRP LIVFDGSSTS TTIKVKKTEN
     GDNDRLRPQP QASATSNTFR KSSDSSSSVS PLVLSSNLPT NNKMEHGNND NKQNHDLTHR
     KSPLGPVRSP PLSPVGATPV KLKRAAPKEE AEASINLKPP EAKRKIQHVT WP