ASHWN_DANRE
ID ASHWN_DANRE Reviewed; 227 AA.
AC Q32LR5; B0S7I9; Q566T1;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 2.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Ashwin;
GN ORFNames=im:6907446, si:dkeyp-118h3.6;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9BVC5}.
CC -!- SIMILARITY: Belongs to the ashwin family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH93350.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAI09458.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX842683; CAQ14278.1; -; Genomic_DNA.
DR EMBL; BC093350; AAH93350.1; ALT_INIT; mRNA.
DR EMBL; BC109457; AAI09458.1; ALT_INIT; mRNA.
DR RefSeq; NP_001137405.1; NM_001143933.1.
DR AlphaFoldDB; Q32LR5; -.
DR SMR; Q32LR5; -.
DR STRING; 7955.ENSDARP00000061584; -.
DR PaxDb; Q32LR5; -.
DR Ensembl; ENSDART00000061585; ENSDARP00000061584; ENSDARG00000042025.
DR GeneID; 553393; -.
DR KEGG; dre:553393; -.
DR ZFIN; ZDB-GENE-050809-8; si:dkeyp-118h3.6.
DR eggNOG; ENOG502S0PQ; Eukaryota.
DR GeneTree; ENSGT00390000007488; -.
DR HOGENOM; CLU_104242_0_0_1; -.
DR InParanoid; Q32LR5; -.
DR OMA; SRWGKRM; -.
DR OrthoDB; 1299864at2759; -.
DR PhylomeDB; Q32LR5; -.
DR TreeFam; TF332084; -.
DR PRO; PR:Q32LR5; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 9.
DR Bgee; ENSDARG00000042025; Expressed in mature ovarian follicle and 21 other tissues.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0072669; C:tRNA-splicing ligase complex; ISS:UniProtKB.
DR GO; GO:0048598; P:embryonic morphogenesis; IEA:InterPro.
DR InterPro; IPR024887; Ashwin.
DR PANTHER; PTHR28359; PTHR28359; 1.
DR Pfam; PF15323; Ashwin; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome.
FT CHAIN 1..227
FT /note="Ashwin"
FT /id="PRO_0000268863"
FT REGION 71..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 161
FT /note="S -> L (in Ref. 2; AAH93350)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 227 AA; 24860 MW; DDCDB5259927D47D CRC64;
MASHRTDRTK NPTSNGDVSK VDLLLHPELL SQEFIQLMLQ ERNIAVSDPE DRDRLTGLYL
QHVIPLPQRE LPRSRWGKRM EKSRPRLSSS STHSSSTDSG RKRPLIVFDG SSTSTGCVKL
KKPDSSSAPV TTDRLKPPVS SVSLTNPIRK LSGASTNCSS SNFSNRTPVS SSGAIPKSPS
NHSNSSVHSN NATSKLKRTS PSKGEPDTAK DIKSPETKKK IQHITWP
