A30_VAR67
ID A30_VAR67 Reviewed; 77 AA.
AC P0DOT9; P21088; P68597;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 16-OCT-2019, sequence version 1.
DT 02-JUN-2021, entry version 6.
DE RecName: Full=Protein A30;
DE AltName: Full=Protein A33;
GN ORFNames=A30L, A33L;
OS Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=587200;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1666548;
RA Shchelkunov S.N., Marennikova S.S., Totmenin A.V., Blinov V.M.,
RA Chizhikov V.E., Gutorov V.V., Safronov P.F., Pozdnyakov S.G.,
RA Shelukhina E.M., Gashnikov P.V., Anjaparidze O.G., Sandakhchiev L.S.;
RT "Creation of a clone library of fragments from the natural variola virus
RT and study of the structural and functional organization of viral genes from
RT a circle of hosts.";
RL Dokl. Akad. Nauk SSSR 321:402-406(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT "Genes of variola and vaccinia viruses necessary to overcome the host
RT protective mechanisms.";
RL FEBS Lett. 319:80-83(1993).
CC -!- FUNCTION: Required for the association between the dense viroplasm and
CC the viral membranes to form the mature virion (MV). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with protein G7; the interaction stabilizes both
CC proteins. {ECO:0000250}.
CC -!- PTM: Phosphorylated by viral F10 kinase. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the chordopoxvirinae A30 family. {ECO:0000305}.
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DR EMBL; X67115; CAA47504.1; -; Genomic_DNA.
DR EMBL; X69198; CAA49078.1; -; Genomic_DNA.
DR PIR; G36851; G36851.
DR RefSeq; NP_042181.1; NC_001611.1.
DR GeneID; 1486511; -.
DR KEGG; vg:1486511; -.
DR Proteomes; UP000002060; Genome.
DR InterPro; IPR009257; Chordopox_A30L.
DR Pfam; PF06015; Chordopox_A30L; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..77
FT /note="Protein A30"
FT /id="PRO_0000099307"
FT REGION 53..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 77 AA; 8745 MW; BC30812604F804E2 CRC64;
MEDLNEANFS HLLINLSNNK DIDAQYASTL SVVHELLSAI NFKIFNINKK SKKNSKSIEQ
HPVVHHAASA GREFNRR