P5_BPPRD
ID P5_BPPRD Reviewed; 340 AA.
AC P22536; Q3T4P0;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 29-SEP-2021, entry version 100.
DE RecName: Full=Spike protein P5;
DE AltName: Full=Protein P5;
GN Name=V;
OS Enterobacteria phage PRD1 (Bacteriophage PRD1).
OC Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC Kalamavirales; Tectiviridae; Alphatectivirus.
OX NCBI_TaxID=10658;
OH NCBI_TaxID=471; Acinetobacter calcoaceticus.
OH NCBI_TaxID=562; Escherichia coli.
OH NCBI_TaxID=584; Proteus mirabilis.
OH NCBI_TaxID=287; Pseudomonas aeruginosa.
OH NCBI_TaxID=294; Pseudomonas fluorescens.
OH NCBI_TaxID=303; Pseudomonas putida (Arthrobacter siderocapsulatus).
OH NCBI_TaxID=90371; Salmonella typhimurium.
OH NCBI_TaxID=666; Vibrio cholerae.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-6.
RX PubMed=2196741; DOI=10.1016/0042-6822(90)90508-o;
RA Bamford J.K.H., Bamford D.H.;
RT "Capsomer proteins of bacteriophage PRD1, a bacterial virus with a
RT membrane.";
RL Virology 177:445-451(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=15946683; DOI=10.1016/j.jmb.2005.04.059;
RA Saren A.M., Ravantti J.J., Benson S.D., Burnett R.M., Paulin L.,
RA Bamford D.H., Bamford J.K.H.;
RT "A snapshot of viral evolution from genome analysis of the tectiviridae
RT family.";
RL J. Mol. Biol. 350:427-440(2005).
RN [3]
RP COLLAGENOUS REGION.
RX PubMed=2320123; DOI=10.1038/344497b0;
RA Bamford D.H., Bamford J.K.H.;
RT "Collagenous proteins multiply.";
RL Nature 344:497-497(1990).
RN [4]
RP FUNCTION.
RX PubMed=10956048; DOI=10.1021/bi000711+;
RA Caldentey J., Tuma R., Bamford D.H.;
RT "Assembly of bacteriophage PRD1 spike complex: role of the multidomain
RT protein P5.";
RL Biochemistry 39:10566-10573(2000).
RN [5]
RP X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 197-339.
RX PubMed=15837420; DOI=10.1016/j.molcel.2005.03.019;
RA Merckel M.C., Huiskonen J.T., Bamford D.H., Goldman A., Tuma R.;
RT "The structure of the bacteriophage PRD1 spike sheds light on the evolution
RT of viral capsid architecture.";
RL Mol. Cell 18:161-170(2005).
CC -!- FUNCTION: In association with P31 and P2, forms the spike complexes
CC located at the 5-fold vertices of the capsid. Essential for viral
CC infectivity. {ECO:0000269|PubMed:10956048}.
CC -!- SUBUNIT: Homotrimer.
CC -!- SUBCELLULAR LOCATION: Virion.
CC -!- DOMAIN: The short collagen-like region is proposed to act as a
CC trimerization signal leading to the fulfillment of the symmetry
CC requirement of the minor capsomer.
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DR EMBL; AY848689; AAX45923.1; -; Genomic_DNA.
DR EMBL; M55568; AAA32446.1; -; Genomic_DNA.
DR PIR; B46345; B46345.
DR RefSeq; NP_040686.1; NC_001421.2.
DR PDB; 1YQ5; X-ray; 2.00 A; A/B=197-340.
DR PDB; 1YQ6; X-ray; 2.40 A; A/B/C=197-340.
DR PDB; 1YQ8; X-ray; 2.60 A; A=142-340.
DR PDBsum; 1YQ5; -.
DR PDBsum; 1YQ6; -.
DR PDBsum; 1YQ8; -.
DR SMR; P22536; -.
DR EvolutionaryTrace; P22536; -.
DR Proteomes; UP000002143; Genome.
DR GO; GO:0098029; C:icosahedral viral capsid, spike; IMP:CACAO.
DR Gene3D; 2.60.120.670; -; 1.
DR InterPro; IPR015044; Phage_PRD1_P5_C.
DR InterPro; IPR015043; Phage_PRD1_P5_spike_N.
DR InterPro; IPR038663; PRD1_P5_C_sf.
DR Pfam; PF08948; DUF1859; 1.
DR Pfam; PF08949; DUF1860; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Capsid protein; Direct protein sequencing;
KW Reference proteome; Virion.
FT INIT_MET 1
FT /note="Removed; by host"
FT /evidence="ECO:0000269|PubMed:2196741"
FT CHAIN 2..340
FT /note="Spike protein P5"
FT /id="PRO_0000165346"
FT DOMAIN 123..141
FT /note="Collagen-like"
FT REGION 2..122
FT /note="Domain-1"
FT REGION 142..340
FT /note="Domain-2"
FT STRAND 148..150
FT /evidence="ECO:0007829|PDB:1YQ8"
FT TURN 153..155
FT /evidence="ECO:0007829|PDB:1YQ8"
FT STRAND 158..161
FT /evidence="ECO:0007829|PDB:1YQ8"
FT STRAND 176..181
FT /evidence="ECO:0007829|PDB:1YQ8"
FT STRAND 184..189
FT /evidence="ECO:0007829|PDB:1YQ8"
FT STRAND 200..207
FT /evidence="ECO:0007829|PDB:1YQ5"
FT TURN 209..212
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 215..217
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 231..242
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 244..249
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 255..264
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 270..279
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 282..289
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 296..305
FT /evidence="ECO:0007829|PDB:1YQ5"
FT TURN 311..313
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 314..325
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 327..329
FT /evidence="ECO:0007829|PDB:1YQ5"
FT STRAND 331..338
FT /evidence="ECO:0007829|PDB:1YQ5"
SQ SEQUENCE 340 AA; 34449 MW; 769A2AFD3FFC6302 CRC64;
MANQQIGGST VTYNGAIPMG GPVAINSVIE IAGTEVLVDL KLDYATGKIS GVQTLYIDLR
DFLGDVTVTM PDTGQRITAR AGTQGYYPVL STNLMKFIVS ATIDGKFPMN FINFPIALGV
WPSGIKGDKG DPGAPGPAGG TVVVEDSGAS FGESLLDTTS EPGKILVKRI SGGSGITVTD
YGDQVEIEAS GGGGGGGGVT DALSLMYSTS TGGPASIAAN ALTDFDLSGA LTVNSVGTGL
TKSAAGIQLA AGKSGLYQIT MTVKNNTVTT GNYLLRVKYG SSDFVVACPA SSLTAGGTIS
LLIYCNVLGV PSLDVLKFSL CNDGAALSNY IINITAAKIN
