P69_MYCGE
ID P69_MYCGE Reviewed; 543 AA.
AC P47533; Q49219; Q49294;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=ABC transport system permease protein p69;
GN Name=p69; OrderedLocusNames=MG291;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-93 AND 406-530.
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
CC -!- FUNCTION: Probably part of a high-affinity transport system.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- DOMAIN: Composed of two homologous domains.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD12453.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; L43967; AAC71512.1; -; Genomic_DNA.
DR EMBL; U02171; AAD12453.1; ALT_INIT; Genomic_DNA.
DR EMBL; U01768; AAD10585.1; -; Genomic_DNA.
DR PIR; B64232; B64232.
DR RefSeq; WP_010869410.1; NC_000908.2.
DR AlphaFoldDB; P47533; -.
DR SMR; P47533; -.
DR STRING; 243273.MG_291; -.
DR EnsemblBacteria; AAC71512; AAC71512; MG_291.
DR KEGG; mge:MG_291; -.
DR eggNOG; COG3639; Bacteria.
DR HOGENOM; CLU_479675_0_0_14; -.
DR OMA; YRFECAL; -.
DR OrthoDB; 1533983at2; -.
DR BioCyc; MGEN243273:G1GJ2-359-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015716; P:organic phosphonate transport; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR017797; Phosphnate-bd.
DR PANTHER; PTHR30043:SF1; PTHR30043:SF1; 2.
DR SUPFAM; SSF161098; SSF161098; 2.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..543
FT /note="ABC transport system permease protein p69"
FT /id="PRO_0000060169"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 482..502
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 510..530
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 74..256
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT CONFLICT 519..530
FT /note="YLIAIEIIFLSV -> LSNCNRNNFSFS (in Ref. 2)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 543 AA; 63076 MW; 86D3787008839987 CRC64;
MITKLFFHQV GDNKKRLIWY WKLLIIIAVL AIVIYSWIDN FSSFNQFGLN VFINNITSLF
TPNLNHEYTL VRFLAQTAFF VTGGSFLGFI FAILFSYWTA FKIQPFYIAL PIRLITIVLR
AFPVLLFGFL FSNLFNKQLA ATLTISWFSF LWNTKYITTF FENSNLKYFF NKKIREGSGF
KAFWTTIFLS ENERLWLFFL YSLEANFRWT TLLSIFGIGG IGQLIVDPLS IRVQFDLVLI
PLVVLITFLI FIEVVVFLLS SFVFEKNSED LRPILKTTVI EKRKWKRIIF ILFIVVLISL
SLANLVTIDY RINDAEFLQD FFNQFFQLKS NLFSSNDPNI NPILMLVKLT TQAISLISLV
VIFSILFGFI SCNLFKKRFS ISFKILLLFV RVVPSILLFR LLDPLFLEAK TTIILVLLIN
HGSSYGQLMS INFNKANQNI INNYKNHGMT KGFILWNYLL VENKPNLINI TSDAYDSVIR
DLILFGSFGG SIIGSRITNF FERAQFDNLG SVTIPLMVYL IAIEIIFLSV RLTRISVFKN
YLY
