ID   P69_TYMVA               Reviewed;         628 AA.
AC   P20131;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   02-JUN-2021, entry version 47.
DE   RecName: Full=69 kDa protein;
DE   AltName: Full=p69;
OS   Turnip yellow mosaic virus (isolate Australia).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Tymoviridae; Tymovirus.
OX   NCBI_TaxID=12155;
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=82359; Cardamine lilacina.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2800335; DOI=10.1016/0042-6822(89)90196-7;
RA   Keese P., Mackenzie A., Gibbs A.;
RT   "Nucleotide sequence of the genome of an Australian isolate of turnip
RT   yellow mosaic tymovirus.";
RL   Virology 172:536-546(1989).
CC   -!- FUNCTION: Acts as a suppressor of RNA-mediated gene silencing, also
CC       known as post-transcriptional gene silencing (PTGS), a mechanism of
CC       plant viral defense that limits the accumulation of viral RNAs.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tymoviridae protein p69 family.
CC       {ECO:0000305}.
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DR   EMBL; J04373; AAA46591.1; -; Genomic_RNA.
DR   PIR; JQ0110; JQ0110.
DR   PRIDE; P20131; -.
DR   Proteomes; UP000008268; Genome.
DR   InterPro; IPR004935; 45/70kDa_tymovirus.
DR   Pfam; PF03251; Tymo_45kd_70kd; 1.
PE   3: Inferred from homology;
KW   Suppressor of RNA silencing.
FT   CHAIN           1..628
FT                   /note="69 kDa protein"
FT                   /id="PRO_0000222944"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          141..492
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          537..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..202
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        203..224
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..239
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..262
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        293..309
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..450
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..614
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   628 AA;  68741 MW;  67CD342A09161D96 CRC64;
     MSNGLPISIG RPCTHDSQRS LSASDSRIHS RFDSLLDTDL PMVHSEGTSA PTQLLRHPNI
     WFGNIPPPPR RPQDNRDFSP LHPLVFPGHH SQLRHVHETQ QVQQTCPGEL KLSGIEELPP
     APQRQHSLPL HITRPSRFPH HFHARRPDVL PSLPDHGPVL AETKPRTSVR QPRSTTRGPS
     FRPILLPEVV HVHDDPPHSS LRPGRSRSRQ LQPTIRRPLL APNQFNSPRQ PPPLSDDPGI
     LGPCPLAPNS TRDPPPRPIT PGPFNTHGVR PLSVLPRAPP RRGLLPNPRR HRTSTGHIPS
     TTASRPTGPP SRLQRPVHLH QSGPHTPDFR PSGIRKDAFL QTGPRLGHLE RLGQSADLRT
     SERTPSTKRR LPRPSEPNCL PSSLPEATLA PSYRHRRSHP LLPNPPAALP PIAYTSGRGK
     IHHSLPKGAL PKEGPPPPPR RLPSPATPPQ SPLRDLGRTP SFPTPPKTST RAPESCIAAP
     PTDIAPLDSD PVLSVRTEVH APERRTFMDP EALRAALAGL PSPPLSVGII RTASQTVLPT
     NSPSPTRHLP PTSSPWILQS PVGEDAIVDS EDDSISSFHS HDFNSPSGPL RSQSPSRFRL
     HLRSPSTSSG IEPWSPASYD YGSAPDTD