ID   P69_TYMVC               Reviewed;         628 AA.
AC   P28478;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   02-JUN-2021, entry version 41.
DE   RecName: Full=69 kDa protein;
DE   AltName: Full=p69;
OS   Turnip yellow mosaic virus (isolate TYMC).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Tymoviridae; Tymovirus.
OX   NCBI_TaxID=31751;
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=82359; Cardamine lilacina.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1731998; DOI=10.1007/bf00034967;
RA   Dreher T.W., Bransom K.L.;
RT   "Genomic RNA sequence of turnip yellow mosaic virus isolate TYMC, a cDNA-
RT   based clone with verified infectivity.";
RL   Plant Mol. Biol. 18:403-406(1992).
CC   -!- FUNCTION: Acts as a suppressor of RNA-mediated gene silencing, also
CC       known as post-transcriptional gene silencing (PTGS), a mechanism of
CC       plant viral defense that limits the accumulation of viral RNAs.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tymoviridae protein p69 family.
CC       {ECO:0000305}.
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DR   EMBL; X16378; CAA34414.1; -; Genomic_RNA.
DR   PIR; S19150; S19150.
DR   InterPro; IPR004935; 45/70kDa_tymovirus.
DR   Pfam; PF03251; Tymo_45kd_70kd; 1.
PE   3: Inferred from homology;
KW   Suppressor of RNA silencing.
FT   CHAIN           1..628
FT                   /note="69 kDa protein"
FT                   /id="PRO_0000222945"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          141..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          347..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          418..507
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          535..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..202
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..239
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..262
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..330
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        431..450
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        538..557
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..614
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   628 AA;  69057 MW;  0DF0C64E8ECBC6DC CRC64;
     MSNGLPISIG RPCTHDSQRS LSAPNSRIHS GFNSLLDTDL PMVHSEGTST PTQLLRHPNI
     WFGNLPPPPR RPQDNRDFSP LHPLVFPGHH SQLRHVHETQ QVQQTCPGKL KLSGAEELPP
     APQRQHSLPL HITRPSRFPH HFHARRPDVL PSVPDHGPVL AETKPRTSVR QPRSATRGPS
     FRPILLPKVV HVHDDPPHSS LRPRGSRSRQ LQPTVRRPLL APNQFHSPRQ PPPLSDDPGI
     LGPRPLAPNS TRDPPPRPIT PGPSNTHGLR PLSVLPRASP RRGLLPNPRR HRTSTGHIPP
     TTTSRPTGPP SRLQRPVHLY QSSPHTPNFR PSSIRKDALL QTGPRLGHLE CLGQPANLRT
     SERSPPTKRR LPRSSEPNRL PKPLPEATLA PSYRHRRSYP FLPNPPAALP SIAYTSSRGK
     IHHSLPKGAL PKEGAPPPPR RLPSPAPHPQ LPLRDLGRTP GFPTPPKTPT RTPESRITAS
     PTDIAPLDSD PVLSVRTEVH APERRTFMDP EALRSALASL PSPPRSVGII HTAPQTVLPA
     NPPSPTRHLP PTSPPWILQS PVGEDAIVDS EDDSISSFYS HDFDSPSGPL RSQSPSRFRL
     YLRSPSTSSG IEPWSPASYD YGSAPDTD