ID   P7_RDVO                 Reviewed;         506 AA.
AC   P22473;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Protein P7;
DE   AltName: Full=55 kDa core protein;
OS   Rice dwarf virus (isolate O) (RDV).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Phytoreovirus.
OX   NCBI_TaxID=142805;
OH   NCBI_TaxID=114194; Alopecurus aequalis.
OH   NCBI_TaxID=90397; Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli).
OH   NCBI_TaxID=94400; Nephotettix cincticeps (Green rice leafhopper) (Selenocephalus cincticeps).
OH   NCBI_TaxID=4530; Oryza sativa (Rice).
OH   NCBI_TaxID=147271; Paspalum.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2313270; DOI=10.1099/0022-1317-71-3-725;
RA   Nakashima K., Kakutani T., Minobe Y.;
RT   "Sequence analysis and product assignment of segment 7 of the rice dwarf
RT   virus genome.";
RL   J. Gen. Virol. 71:725-729(1990).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS).
RX   PubMed=14527391; DOI=10.1016/j.str.2003.08.012;
RA   Nakagawa A., Miyazaki N., Taka J., Naitow H., Ogawa A., Fujimoto Z.,
RA   Mizuno H., Higashi T., Watanabe Y., Omura T., Cheng R.H., Tsukihara T.;
RT   "The atomic structure of rice dwarf virus reveals the self-assembly
RT   mechanism of component proteins.";
RL   Structure 11:1227-1238(2003).
RN   [3]
RP   PROTEIN SEQUENCE OF 1-12; 22-33; 82-99; 128-137; 193-210; 240-259; 300-334;
RP   356-370; 380-391; 414-432 AND 453-476, IDENTIFICATION, AND RNA-BINDING.
RX   PubMed=15645082; DOI=10.1093/abbs/37.1.55;
RA   Zhong B.X., Shen Y.W., Omura T.;
RT   "RNA-binding domain of the key structural protein P7 for the Rice dwarf
RT   virus particle assembly.";
RL   Acta Biochim. Biophys. Sin. 37:55-60(2005).
RN   [4]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=20190042; DOI=10.1093/jb/mvq017;
RA   Miyazaki N., Wu B., Hagiwara K., Wang C.Y., Xing L., Hammar L.,
RA   Higashiura A., Tsukihara T., Nakagawa A., Omura T., Cheng R.H.;
RT   "The functional organization of the internal components of Rice dwarf
RT   virus.";
RL   J. Biochem. 147:843-850(2010).
CC   -!- FUNCTION: Probable component of the transcriptional machinery present
CC       in the inner capsid. Displays dsRNA binding activity and may play an
CC       important role in the sorting of viral RNA and virion assembly.
CC       Together with the RNA-directed RNA polymerase P1 and capping enzyme P5,
CC       forms an transcriptional complex positioned near the channels situated
CC       at each of the five-fold vertices of the core.
CC       {ECO:0000269|PubMed:20190042}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305|PubMed:20190042}. Host
CC       cytoplasm {ECO:0000250}. Note=Located inside the inner capsid. Found in
CC       the interior of spherical cytoplasmic structures, called virus
CC       factories, that appear early after infection and are the site of viral
CC       replication and packaging (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phytoreovirus protein P7 family.
CC       {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Virus Particle ExploreR db; Note=Icosahedral capsid
CC       structure;
CC       URL="https://viperdb.scripps.edu/Info_Page.php?VDB=1uf2";
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DR   EMBL; D00639; BAA00535.1; -; Genomic_RNA.
DR   PDB; 1UF2; X-ray; 3.50 A; K=1-506.
DR   PDBsum; 1UF2; -.
DR   SMR; P22473; -.
DR   PRIDE; P22473; -.
DR   EvolutionaryTrace; P22473; -.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   DisProt; DP02487; -.
DR   InterPro; IPR009873; Phytoreo_S7.
DR   Pfam; PF07236; Phytoreo_S7; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Capsid protein; Direct protein sequencing; Host cytoplasm;
KW   RNA-binding; Virion.
FT   CHAIN           1..506
FT                   /note="Protein P7"
FT                   /id="PRO_0000222792"
FT   REGION          128..249
FT                   /note="RNA-binding"
FT   REGION          325..355
FT                   /note="RNA-binding"
FT   STRAND          292..297
FT                   /evidence="ECO:0007829|PDB:1UF2"
SQ   SEQUENCE   506 AA;  55342 MW;  1A5D84B7A241037A CRC64;
     MSAIVGLCLL SEKVVLSRSL TDEVSKLYKL NRGNVKEPRK YATERMSTQS KPVALQVPVS
     TIILDYKNED FIKQNPTYSA MDIIGSPSNT APQTAFQSIM PSLSALFNTP FIQGAFRHRI
     ISSMGPEISY LVMVIGPPSG FMDTPNVSSA QSSVHTVSNA DVDLNDIIAI NSTMAKSTKL
     VSASTLQAML VNDVYDRCMD LDGILLSQAL PFFRNYVNVQ SKGSLPPAVA ACLNTPIKEL
     FSMGSGKREP LALEFRKDNE GQCIGIVLPK GHEGDTLSSR YPAVFINESE PFSDKERSEL
     SELKRTDSDA YEKLYSETIS KHVSDGSYGN RVIISHKMSR LSNGGVKIIG RFKISDFNTV
     KKNLSSRSGE IDSAKEQWEA LSGNGLVTDS NISMLHDKIL DTITSNKPGV VLRDGNKKSE
     NIVVCFKNGF PNKKHSLLQL TKNGISVVSL DELTDAGILV ESTGPDRVRR SPKVLANKLS
     SFKGRKVTLD VDNMSTEALI QKLSTL