ID   P8A7_DICDI              Reviewed;         138 AA.
AC   P11022; Q55CL0;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Membrane protein P8A7;
GN   Name=pmpA; Synonyms=P8A7; ORFNames=DDB_G0269170;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=AX2;
RX   PubMed=3336356; DOI=10.1128/mcb.8.1.153-159.1988;
RA   Maniak M., Nellen W.;
RT   "A developmentally regulated membrane protein gene in Dictyostelium
RT   discoideum is also induced by heat shock and cold shock.";
RL   Mol. Cell. Biol. 8:153-159(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AX2;
RX   PubMed=2356118; DOI=10.1093/nar/18.11.3211;
RA   Maniak M., Nellen W.;
RT   "Two separable promoters control different aspects of expression of a
RT   Dictyostelium gene.";
RL   Nucleic Acids Res. 18:3211-3217(1990).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AX2;
RX   PubMed=2216709; DOI=10.1093/nar/18.18.5375;
RA   Maniak M., Nellen W.;
RT   "Evidence for a feedback regulated back-up promoter which controls
RT   permanent expression of a Dictyostelium gene.";
RL   Nucleic Acids Res. 18:5375-5380(1990).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Developmentally regulated, is also induced by heat shock and
CC       cold shock.
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DR   EMBL; M19416; AAA33225.1; -; mRNA.
DR   EMBL; X51947; CAA36209.1; -; Genomic_DNA.
DR   EMBL; AAFI02000005; EAL71935.1; -; Genomic_DNA.
DR   PIR; S14689; BWDOP8.
DR   RefSeq; XP_646471.1; XM_641379.1.
DR   AlphaFoldDB; P11022; -.
DR   SMR; P11022; -.
DR   PaxDb; P11022; -.
DR   EnsemblProtists; EAL71935; EAL71935; DDB_G0269170.
DR   GeneID; 8617432; -.
DR   KEGG; ddi:DDB_G0269170; -.
DR   dictyBase; DDB_G0269170; pmpA.
DR   eggNOG; ENOG502SF3W; Eukaryota.
DR   HOGENOM; CLU_1858994_0_0_1; -.
DR   InParanoid; P11022; -.
DR   OMA; YVALEFI; -.
DR   PRO; PR:P11022; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR013714; Golgi_TVP15.
DR   PANTHER; PTHR28128; PTHR28128; 1.
DR   Pfam; PF08507; COPI_assoc; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..138
FT                   /note="Membrane protein P8A7"
FT                   /id="PRO_0000058148"
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   138 AA;  15056 MW;  C22A87ACF646FE25 CRC64;
     MSQSTAYIIL NILVILAGCF ITACGIYLFV NGLFHSIIGF VLGIYYLLAG VCIVLLEIVF
     PQKLVNLFGF YTYWFGKGAL ISLIGLLILG NSGFFLAAGI IVIAVGIVCM IFHFLLGCPR
     PLINRSVERK PEPQGQHA