ID   P8_WTV                  Reviewed;         427 AA.
AC   P17380;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   12-AUG-2020, entry version 67.
DE   RecName: Full=Outer capsid protein P8;
DE   AltName: Full=Structural protein P8;
OS   Wound tumor virus (WTV).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Phytoreovirus.
OX   NCBI_TaxID=10987;
OH   NCBI_TaxID=4058; Catharanthus roseus (Madagascar periwinkle) (Vinca rosea).
OH   NCBI_TaxID=47083; Melilotus officinalis (Yellow sweet clover) (Trifolium officinale).
OH   NCBI_TaxID=60916; Trifolium incarnatum (Crimson clover).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2543127; DOI=10.1016/0042-6822(89)90443-1;
RA   Xu Z., Anzola J.V., Nalin C.M., Nuss D.L.;
RT   "The 3'-terminal sequence of a wound tumor virus transcript can influence
RT   conformational and functional properties associated with the 5'-terminus.";
RL   Virology 170:511-522(1989).
CC   -!- FUNCTION: Capsid protein which self-assembles to form the outer
CC       icosahedral capsid with a T=13 symmetry, about 70 nm in diameter and
CC       consisting of 780 molecules capsid proteins.
CC   -!- SUBUNIT: Homotrimer. Homomultimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host cytoplasm
CC       {ECO:0000250}. Note=Found in the peripheral regions of spherical
CC       cytoplasmic structures, called virus factories, that appear early after
CC       infection and are the site of viral replication and packaging.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phytoreovirus outer capsid protein P8
CC       family. {ECO:0000305}.
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DR   EMBL; J04344; AAA48503.1; -; Genomic_RNA.
DR   PIR; A30231; MWXRWV.
DR   SMR; P17380; -.
DR   Proteomes; UP000242823; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR   GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR   GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR   InterPro; IPR008980; Capsid_hemagglutn.
DR   InterPro; IPR009807; Phytoreo_P8.
DR   InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR   Pfam; PF07124; Phytoreo_P8; 1.
DR   SUPFAM; SSF48345; SSF48345; 1.
DR   SUPFAM; SSF49818; SSF49818; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host cytoplasm; Outer capsid protein; Virion.
FT   CHAIN           1..427
FT                   /note="Outer capsid protein P8"
FT                   /id="PRO_0000222767"
SQ   SEQUENCE   427 AA;  48065 MW;  FA29E2A48AA6AB8C CRC64;
     MSRQNWVETS ALVECISEYI VRSYGDTFIG LTSTDLSTLS NLLSNLSIAN VGFLNDLRTP
     LQNMSNEFVD FLSTTDRCGF MLRPIWFDSD INPAVTDNFV NSYIKLRNSV PVSDVIRQVN
     NLSLHNDVVL KIYSVQNAII RALDPPYGTK VDPTNLFRAT ALKPSNYGQR RSLCTQLGAG
     VEAVDFFVSE RGRMVFGRRS PNALQAAQYD INVPNFWSVL DVTNARVYFT NTFLGCTITN
     VQVNAQNGQN PVAFIRVNTD QNDINVDSDA IVSFSLAGGV INVTTAVPMT GFAIAIEGDF
     HFQMNRCQSY YTGVSITLGA QVPIDDFGIM KHLEIFRMRL LACGQAEMFA ESMNRLTMQL
     IANYTQDNFN PNAVAFATPW YRISERFGVI LSFIDQNINL QTRRLMVRHL WVIYSFIAVF
     GRYYNIN