A30_VARV
ID A30_VARV Reviewed; 77 AA.
AC P0DOU0; P21088; P68597;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 16-OCT-2019, sequence version 1.
DT 29-SEP-2021, entry version 10.
DE RecName: Full=Protein A30;
DE AltName: Full=Protein A33;
GN ORFNames=A30L, A33L;
OS Variola virus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10255;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Harvey;
RX PubMed=1331292; DOI=10.1099/0022-1317-73-11-2887;
RA Aguado B., Selmes I.P., Smith G.L.;
RT "Nucleotide sequence of 21.8 kbp of variola major virus strain Harvey and
RT comparison with vaccinia virus.";
RL J. Gen. Virol. 73:2887-2902(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Bangladesh-1975;
RX PubMed=8264798; DOI=10.1038/366748a0;
RA Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C.,
RA Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A.,
RA Cavallaro K.F., Kerlavage A.R., Mahy B.W.J., Venter J.C.;
RT "Potential virulence determinants in terminal regions of variola smallpox
RT virus genome.";
RL Nature 366:748-751(1993).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Garcia-1966;
RA Shchelkunov S.N., Totmenin A.V., Resenchuk S.M., Blinov V.M.,
RA Sandakhchiev L.S.;
RL Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the association between the dense viroplasm and
CC the viral membranes to form the mature virion (MV). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with protein G7; the interaction stabilizes both
CC proteins. {ECO:0000250}.
CC -!- PTM: Phosphorylated by viral F10 kinase. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the chordopoxvirinae A30 family. {ECO:0000305}.
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DR EMBL; L22579; AAA60885.1; -; Genomic_DNA.
DR EMBL; X76266; CAA53859.1; -; Genomic_DNA.
DR PIR; G72167; G72167.
DR PIR; T28575; T28575.
DR RefSeq; NP_042181.1; NC_001611.1.
DR GeneID; 1486511; -.
DR KEGG; vg:1486511; -.
DR Proteomes; UP000119805; Genome.
DR InterPro; IPR009257; Chordopox_A30L.
DR Pfam; PF06015; Chordopox_A30L; 1.
PE 3: Inferred from homology;
KW Phosphoprotein.
FT CHAIN 1..77
FT /note="Protein A30"
FT /id="PRO_0000448162"
FT REGION 53..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 77 AA; 8745 MW; BC30812604F804E2 CRC64;
MEDLNEANFS HLLINLSNNK DIDAQYASTL SVVHELLSAI NFKIFNINKK SKKNSKSIEQ
HPVVHHAASA GREFNRR