PA1C_ODOVE
ID PA1C_ODOVE Reviewed; 68 AA.
AC Q1JS94;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Palustrin-1c;
DE Short=pal1c;
DE Flags: Precursor;
OS Odorrana versabilis (Chinese bamboo leaf odorous frog) (Rana versabilis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Odorrana.
OX NCBI_TaxID=326940;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND MASS SPECTROMETRY.
RC TISSUE=Skin secretion;
RX PubMed=16621152; DOI=10.1016/j.peptides.2006.02.009;
RA Chen T., Zhou M., Rao P., Walker B., Shaw C.;
RT "The Chinese bamboo leaf odorous frog (Rana (odorrana) versabilis) and
RT north american rana frogs share the same families of skin antimicrobial
RT peptides.";
RL Peptides 27:1738-1744(2006).
CC -!- FUNCTION: Antimicrobial peptide. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC -!- MASS SPECTROMETRY: Mass=2873.32; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:16621152};
CC -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC Brevinin subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM113507; CAJ34603.1; -; mRNA.
DR AlphaFoldDB; Q1JS94; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR InterPro; IPR012521; Antimicrobial_frog_2.
DR InterPro; IPR004275; Frog_antimicrobial_propeptide.
DR Pfam; PF08023; Antimicrobial_2; 1.
DR Pfam; PF03032; FSAP_sig_propep; 1.
PE 1: Evidence at protein level;
KW Amphibian defense peptide; Antibiotic; Antimicrobial;
KW Cleavage on pair of basic residues; Disulfide bond; Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT PROPEP 23..39
FT /id="PRO_0000268221"
FT PEPTIDE 42..68
FT /note="Palustrin-1c"
FT /id="PRO_0000268222"
FT DISULFID 62..68
SQ SEQUENCE 68 AA; 7524 MW; 293B6893304D565B CRC64;
MFTMKKSLLL LFFLGTISLS LCEEERGADE EEGDGEKLTK RALSILRGLE KLAKMGIALT
NCKATKKC