ASIL2_ARATH
ID ASIL2_ARATH Reviewed; 443 AA.
AC Q9LJG8;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Trihelix transcription factor ASIL2 {ECO:0000305};
DE AltName: Full=6B-interacting protein 1-like 2 {ECO:0000303|PubMed:21330492};
DE AltName: Full=Trihelix DNA-binding protein ASIL2 {ECO:0000305};
GN Name=ASIL2 {ECO:0000303|PubMed:21330492};
GN OrderedLocusNames=At3g14180 {ECO:0000312|Araport:AT3G14180};
GN ORFNames=MAG2.16 {ECO:0000312|EMBL:BAB02984.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=21330492; DOI=10.1104/pp.110.171355;
RA Willmann M.R., Mehalick A.J., Packer R.L., Jenik P.D.;
RT "MicroRNAs regulate the timing of embryo maturation in Arabidopsis.";
RL Plant Physiol. 155:1871-1884(2011).
CC -!- FUNCTION: Transcription regulator that may repress the maturation
CC program during early embryogenesis. {ECO:0000269|PubMed:21330492}.
CC -!- INTERACTION:
CC Q9LJG8; Q8VZI9: At3g11100; NbExp=3; IntAct=EBI-4427947, EBI-1998580;
CC Q9LJG8; Q8GXR6: At3g58630/F14P22_220; NbExp=3; IntAct=EBI-4427947, EBI-4457957;
CC Q9LJG8; F4IV99: CHR5; NbExp=4; IntAct=EBI-4427947, EBI-15203078;
CC Q9LJG8; O65426: LOL2; NbExp=3; IntAct=EBI-4427947, EBI-15192119;
CC Q9LJG8; F4K0Q7: MOP10.9; NbExp=3; IntAct=EBI-4427947, EBI-15192203;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9SYG2,
CC ECO:0000255|PROSITE-ProRule:PRU00768}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:21330492}.
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DR EMBL; AP000600; BAB02984.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75483.1; -; Genomic_DNA.
DR EMBL; AY072187; AAL60009.1; -; mRNA.
DR EMBL; AY113853; AAM44901.1; -; mRNA.
DR RefSeq; NP_188034.1; NM_112274.4.
DR AlphaFoldDB; Q9LJG8; -.
DR SMR; Q9LJG8; -.
DR BioGRID; 5969; 33.
DR IntAct; Q9LJG8; 33.
DR STRING; 3702.AT3G14180.1; -.
DR iPTMnet; Q9LJG8; -.
DR PaxDb; Q9LJG8; -.
DR PRIDE; Q9LJG8; -.
DR ProteomicsDB; 246513; -.
DR EnsemblPlants; AT3G14180.1; AT3G14180.1; AT3G14180.
DR GeneID; 820635; -.
DR Gramene; AT3G14180.1; AT3G14180.1; AT3G14180.
DR KEGG; ath:AT3G14180; -.
DR Araport; AT3G14180; -.
DR TAIR; locus:2087472; AT3G14180.
DR eggNOG; KOG4282; Eukaryota.
DR HOGENOM; CLU_042856_1_0_1; -.
DR InParanoid; Q9LJG8; -.
DR OMA; AYEQTEN; -.
DR OrthoDB; 1221690at2759; -.
DR PhylomeDB; Q9LJG8; -.
DR PRO; PR:Q9LJG8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LJG8; baseline and differential.
DR Genevisible; Q9LJG8; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0010431; P:seed maturation; IMP:TAIR.
DR InterPro; IPR044823; ASIL1/2-like.
DR InterPro; IPR040257; ASIL2.
DR InterPro; IPR044822; Myb_DNA-bind_4.
DR PANTHER; PTHR31307; PTHR31307; 2.
DR PANTHER; PTHR31307:SF54; PTHR31307:SF54; 2.
DR Pfam; PF13837; Myb_DNA-bind_4; 1.
PE 1: Evidence at protein level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..443
FT /note="Trihelix transcription factor ASIL2"
FT /id="PRO_0000430503"
FT DOMAIN 84..144
FT /note="Myb-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 360..414
FT /evidence="ECO:0000255"
FT MOTIF 290..303
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 12..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 443 AA; 48314 MW; 8CCC2EE23F0B1959 CRC64;
MEDDEDIRSQ GSDSPDPSSS PPAGRITVTV ASAGPPSYSL TPPGNSSQKD PDALALALLP
IQASGGGNNS SGRPTGGGGR EDCWSEAATA VLIDAWGERY LELSRGNLKQ KHWKEVAEIV
SSREDYGKIP KTDIQCKNRI DTVKKKYKQE KVRIANGGGR SRWVFFDKLD RLIGSTAKIP
TATSGVSGPV GGLHKIPMGI PMGSRSNLYH QQAKAATPPF NNLDRLIGAT ARVSAASFGG
SGGGGGGGSV NVPMGIPMSS RSAPFGQQGR TLPQQGRTLP QQQQQGMMVK RCSESKRWRF
RKRNASDSDS ESEAAMSDDS GDSLPPPPLS KRMKTEEKKK QDGDGVGNKW RELTRAIMRF
GEAYEQTENA KLQQVVEMEK ERMKFLKELE LQRMQFFVKT QLEISQLKQQ HGRRMGNTSN
DHHHSRKNNI NAIVNNNNDL GNN
