PA50F_BISBO
ID PA50F_BISBO Reviewed; 8 AA.
AC P85324;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 17.
DE RecName: Full=Pregnancy-associated glycoprotein 50F;
DE EC=3.4.23.-;
DE AltName: Full=EbPAG-F 50 kDa;
DE Flags: Fragment;
OS Bison bonasus (European bison).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bison.
OX NCBI_TaxID=9902;
RN [1]
RP PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND
RP GLYCOSYLATION.
RC TISSUE=Placenta;
RX PubMed=18538513; DOI=10.1016/j.anireprosci.2008.04.021;
RA Kiewisz J., Melo de Sousa N., Beckers J.-F.M.P., Panasiewicz G.,
RA Gizejewski Z., Szafranska B.;
RT "Identification of multiple pregnancy-associated glycoproteins (PAGs)
RT purified from the European bison (Eb; Bison bonasus L.) placentas.";
RL Anim. Reprod. Sci. 112:229-250(2009).
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Chorionic epithelium (trophectoderm) and placental
CC cotyledons. {ECO:0000269|PubMed:18538513}.
CC -!- DEVELOPMENTAL STAGE: Expressed at 60 dpc.
CC {ECO:0000269|PubMed:18538513}.
CC -!- PTM: Glycosylated. {ECO:0000269|PubMed:18538513}.
CC -!- MISCELLANEOUS: On the 2D-gel the determined pI of this protein is: 4.7,
CC its MW is: 50 kDa. {ECO:0000269|PubMed:18538513}.
CC -!- SIMILARITY: Belongs to the peptidase A1 family. {ECO:0000255}.
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DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Aspartyl protease; Direct protein sequencing; Glycoprotein; Hydrolase;
KW Protease; Secreted.
FT CHAIN 1..>8
FT /note="Pregnancy-associated glycoprotein 50F"
FT /id="PRO_0000314066"
FT NON_TER 8
FT /evidence="ECO:0000303|PubMed:18538513"
SQ SEQUENCE 8 AA; 847 MW; DAB8640735B046C5 CRC64;
SQISLRGS