ID   PAAF1_CHICK             Reviewed;         392 AA.
AC   Q5ZK69;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Proteasomal ATPase-associated factor 1;
DE   AltName: Full=WD repeat-containing protein 71;
GN   Name=PAAF1; Synonyms=WDR71; ORFNames=RCJMB04_12m19;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Inhibits proteasome 26S assembly and activity by impairing
CC       the association of the 19S regulatory complex with the 20S core.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with proteasome 26S subunit ATPases. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat PAAF1/RPN14 family. {ECO:0000305}.
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DR   EMBL; AJ720215; CAG31874.1; -; mRNA.
DR   RefSeq; NP_001026006.1; NM_001030835.1.
DR   AlphaFoldDB; Q5ZK69; -.
DR   SMR; Q5ZK69; -.
DR   STRING; 9031.ENSGALP00000027934; -.
DR   PaxDb; Q5ZK69; -.
DR   PRIDE; Q5ZK69; -.
DR   GeneID; 419061; -.
DR   KEGG; gga:419061; -.
DR   CTD; 80227; -.
DR   VEuPathDB; HostDB:geneid_419061; -.
DR   eggNOG; KOG0266; Eukaryota.
DR   InParanoid; Q5ZK69; -.
DR   OrthoDB; 736374at2759; -.
DR   PhylomeDB; Q5ZK69; -.
DR   PRO; PR:Q5ZK69; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Proteasome; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..392
FT                   /note="Proteasomal ATPase-associated factor 1"
FT                   /id="PRO_0000235686"
FT   REPEAT          90..129
FT                   /note="WD 1"
FT   REPEAT          132..171
FT                   /note="WD 2"
FT   REPEAT          174..213
FT                   /note="WD 3"
FT   REPEAT          278..316
FT                   /note="WD 4"
FT   REPEAT          359..392
FT                   /note="WD 5"
SQ   SEQUENCE   392 AA;  42373 MW;  DCB68F477A496EB2 CRC64;
     MAATLRIQSD WSQALRRDEG EAWLSCRSPG KPTLYGSLTR RGLSTEGVPD IAASEGFVVG
     EVTKKSILIS CPHENVSTKF LAPYTTFSRI HQKSITCLDI SSGGGLGVST STDGTMKIWQ
     AANGEIRRLL EGHVYDVNCC RFFPSGLVVL SGGMDAQLKI WSAEDASCVV TFKGHKGGIL
     DTAIVDRGRN VLSCSRDGTA RLWDCGKSSC LAVIADCGSP INGIAVGTAD DSVNLGTPEK
     APSEREIGTE GKILLLARED KKLQGVGLQS RQPVFLFDGS DAFNCCTFLS STYFLAGTQD
     GNIYQLDVRN TNAPIQIIHR SGAPVLSLLP YRDGFIASQG DGTCFIVQQD LDYVIDLTEA
     DCDPVYKVAP WEKQIYTCCR DGVVRRYQLG DL