PAAY_ECOLI
ID PAAY_ECOLI Reviewed; 196 AA.
AC P77181; O53020;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Phenylacetic acid degradation protein PaaY;
GN Name=paaY; Synonyms=ydbZ; OrderedLocusNames=b1400, JW1395;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=W / ATCC 11105 / DSM 1900;
RX PubMed=9748275; DOI=10.1074/jbc.273.40.25974;
RA Ferrandez A., Minambres B., Garcia B., Olivera E.R., Luengo J.M.,
RA Garcia J.L., Diaz E.;
RT "Catabolism of phenylacetic acid in Escherichia coli. Characterization of a
RT new aerobic hybrid pathway.";
RL J. Biol. Chem. 273:25974-25986(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- PATHWAY: Aromatic compound metabolism; phenylacetate degradation.
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000305}.
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DR EMBL; X97452; CAA66102.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74482.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15008.1; -; Genomic_DNA.
DR PIR; C64891; C64891.
DR RefSeq; NP_415918.1; NC_000913.3.
DR RefSeq; WP_001123464.1; NZ_LN832404.1.
DR AlphaFoldDB; P77181; -.
DR SMR; P77181; -.
DR IntAct; P77181; 6.
DR STRING; 511145.b1400; -.
DR jPOST; P77181; -.
DR PaxDb; P77181; -.
DR PRIDE; P77181; -.
DR EnsemblBacteria; AAC74482; AAC74482; b1400.
DR EnsemblBacteria; BAA15008; BAA15008; BAA15008.
DR GeneID; 945965; -.
DR KEGG; ecj:JW1395; -.
DR KEGG; eco:b1400; -.
DR PATRIC; fig|1411691.4.peg.871; -.
DR EchoBASE; EB3510; -.
DR eggNOG; COG0663; Bacteria.
DR HOGENOM; CLU_064827_4_2_6; -.
DR InParanoid; P77181; -.
DR OMA; MPVYQID; -.
DR PhylomeDB; P77181; -.
DR BioCyc; EcoCyc:G6721-MON; -.
DR BioCyc; MetaCyc:G6721-MON; -.
DR UniPathway; UPA00930; -.
DR PRO; PR:P77181; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016289; F:CoA hydrolase activity; IDA:EcoCyc.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0010124; P:phenylacetate catabolic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR011974; PaaY.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR Pfam; PF00132; Hexapep; 2.
DR SUPFAM; SSF51161; SSF51161; 1.
DR TIGRFAMs; TIGR02287; PaaY; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; Transferase.
FT CHAIN 1..196
FT /note="Phenylacetic acid degradation protein PaaY"
FT /id="PRO_0000068731"
FT VARIANT 75
FT /note="G -> E (in strain: W)"
FT VARIANT 179
FT /note="I -> V (in strain: W)"
FT VARIANT 182
FT /note="G -> N (in strain: W)"
SQ SEQUENCE 196 AA; 21325 MW; FA3454F5AA0910DB CRC64;
MPIYQIDGLT PVVPEESFVH PTAVLIGDVI LGKGVYVGPN ASLRGDFGRI VVKDGANIQD
NCVMHGFPEQ DTVVGEDGHI GHSAILHGCI IRRNALVGMN AVVMDGAVIG ENSIVGASAF
VKAKAEMPAN YLIVGSPAKA IRELSEQELA WKKQGTHEYQ VLVTRCKQTL HQVEPLREIE
PGRKRLVFDE NLRPKQ
