ID   PABL_STRGR              Reviewed;         307 AA.
AC   P33585;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Protein Y;
DE   AltName: Full=ORF-3;
DE   Flags: Fragment;
OS   Streptomyces griseus.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IMRU 3570;
RX   PubMed=8472954; DOI=10.1016/0378-1119(93)90602-y;
RA   Criado L.M., Martin J.F., Gil J.A.;
RT   "The pab gene of Streptomyces griseus, encoding p-aminobenzoic acid
RT   synthase, is located between genes possibly involved in candicidin
RT   biosynthesis.";
RL   Gene 126:135-139(1993).
CC   -!- FUNCTION: May be a p-aminobenzoic acid-CoA ligase that activates PabA
CC       to start the biosynthesis of candicidin.
CC   -!- PATHWAY: Antibiotic biosynthesis; candicidin biosynthesis.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000305}.
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DR   EMBL; M93058; -; NOT_ANNOTATED_CDS; Unassigned_DNA.
DR   PIR; PN0470; PN0470.
DR   AlphaFoldDB; P33585; -.
DR   SMR; P33585; -.
DR   UniPathway; UPA00101; -.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.12780; -; 1.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; ANL_N_sf.
DR   Pfam; PF00501; AMP-binding; 1.
PE   3: Inferred from homology;
KW   Antibiotic biosynthesis; Ligase.
FT   CHAIN           1..>307
FT                   /note="Protein Y"
FT                   /id="PRO_0000193179"
FT   NON_TER         307
SQ   SEQUENCE   307 AA;  32391 MW;  7711F77C64FF2477 CRC64;
     MVPVHAHDYV TDPPSTTGRT LDGLTLPRVF ADAVHRGGDA VALVDGEYAL TWSAWRTAVD
     ALARGLQESG VVSGDVVALH LPNSWEYLTL HLAAASVGAV TMPVHQGNAP SDVRALLERV
     RPAAVVLTAR TQEGGGPLTG PALREVLPEL RAVLVTGDAA GEGTETVTEM LERWSGEDPL
     PVEVRPDSPF LLLPSSGTTS ARPKICLHSH EGLLTNSRAA TEDTADAYAG TLITACPLTH
     CFGLQSAYSA LFRAGRQVLL SGWDVGRFLE LARRERPSVV VAVPASCTTW SPGCARTRTA
     PASARPD