PAB_ARATH
ID PAB_ARATH Reviewed; 330 AA.
AC Q94JY0; O49495;
DT 10-OCT-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=Protein IN CHLOROPLAST ATPASE BIOGENESIS, chloroplastic {ECO:0000303|PubMed:25775508};
DE Flags: Precursor;
GN Name=PAB {ECO:0000303|PubMed:25775508};
GN OrderedLocusNames=At4g34090 {ECO:0000312|Araport:AT4G34090};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, INTERACTION WITH ATPC1, SUBCELLULAR LOCATION, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=25775508; DOI=10.1073/pnas.1413392111;
RA Mao J., Chi W., Ouyang M., He B., Chen F., Zhang L.;
RT "PAB is an assembly chaperone that functions downstream of chaperonin 60 in
RT the assembly of chloroplast ATP synthase coupling factor 1.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:4152-4157(2015).
CC -!- FUNCTION: Involved in the assembly of the F(1) ATP synthase in
CC chloroplast thylakoid membranes (PubMed:25775508). Functions downstream
CC of the CPN60 chaperones to promote assembly of the catalytically active
CC core of the chloroplast ATP synthase (PubMed:25775508). Assists the
CC assembly of the ATP synthase gamma subunit into the active F(1) core
CC downstream of CPN60-mediated folding, which is critical for the
CC biogenesis of the chloroplast ATP synthase (PubMed:25775508).
CC {ECO:0000269|PubMed:25775508}.
CC -!- SUBUNIT: Interacts with ATPC1. {ECO:0000269|PubMed:25775508}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC {ECO:0000269|PubMed:25775508}.
CC -!- DISRUPTION PHENOTYPE: Severe growth defects, and inability to flower
CC and produce seeds. {ECO:0000269|PubMed:25775508}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA17563.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB80126.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL021961; CAA17563.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161584; CAB80126.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE86319.1; -; Genomic_DNA.
DR EMBL; AF370544; AAK48971.1; -; mRNA.
DR EMBL; AY081498; AAM10060.1; -; mRNA.
DR EMBL; AK229149; BAF01023.1; -; mRNA.
DR PIR; T05427; T05427.
DR RefSeq; NP_567951.1; NM_119570.4.
DR AlphaFoldDB; Q94JY0; -.
DR PRIDE; Q94JY0; -.
DR DNASU; 829555; -.
DR EnsemblPlants; AT4G34090.1; AT4G34090.1; AT4G34090.
DR GeneID; 829555; -.
DR Gramene; AT4G34090.1; AT4G34090.1; AT4G34090.
DR KEGG; ath:AT4G34090; -.
DR Araport; AT4G34090; -.
DR OMA; NIAQWED; -.
DR PhylomeDB; Q94JY0; -.
DR PRO; PR:Q94JY0; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q94JY0; baseline and differential.
DR GO; GO:0009570; C:chloroplast stroma; IDA:UniProtKB.
DR GO; GO:0033614; P:chloroplast proton-transporting ATP synthase complex assembly; IMP:UniProtKB.
DR InterPro; IPR045287; PAB.
DR PANTHER; PTHR35115; PTHR35115; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..35
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 36..330
FT /note="Protein IN CHLOROPLAST ATPASE BIOGENESIS,
FT chloroplastic"
FT /id="PRO_0000445239"
SQ SEQUENCE 330 AA; 36909 MW; 0F482FD86909990F CRC64;
MGSISMHITP STALPIRHFR ARVSCCSSGH VSFIKDVAAT EPPMHLHHLL KVLQTRGETI
ISPGAKQGLI PLAIPLSKNS SGSVTALLRW PTAPPGMDMP VVEVWRSGVR LIARNVDEYI
HRILVEEDAQ ELTELYRASG EAGEKLYEKG AFAESEIDNL DVYVLKKVGL FPDLLERKVL
RHFDEGDHVS AMVTGEFYTK KDLFPGFGRP FVYYANILQK VGRNVEAKDA ARVALRSPWW
TLGCPYEEVA SIAQWEDEQI EFIREKVSDE GRFEDLHKGK APIQVALDVA AFLLDLASIE
GTWSESLNHI AKCYEEAGLH HISNFVLYTD
