ID   PACA_BPP1               Reviewed;         397 AA.
AC   P28813;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Terminase A protein;
DE   AltName: Full=DNA-packaging protein A;
DE   AltName: Full=PACase A protein;
GN   Name=pacA;
OS   Escherichia phage P1 (Bacteriophage P1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Punavirus.
OX   NCBI_TaxID=2886926;
OH   NCBI_TaxID=543; Enterobacteriaceae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1538406; DOI=10.1016/0022-2836(92)90256-j;
RA   Skorupski K., Pierce J.C., Sauer B., Sternberg N.;
RT   "Bacteriophage P1 genes involved in the recognition and cleavage of the
RT   phage packaging site (pac).";
RL   J. Mol. Biol. 223:977-989(1992).
CC   -!- FUNCTION: Necessary for recognition and cleavage of the phage packaging
CC       site (pac), together with the pacB protein. Both are probably the two
CC       major subunits of the phage PACase.
CC   -!- SUBUNIT: Multimer of two distinct subunits. {ECO:0000250}.
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DR   EMBL; M74046; AAA21723.1; -; Genomic_DNA.
DR   PIR; S21780; S21780.
DR   SMR; P28813; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   DNA-binding; Hydrolase; Nuclease.
FT   CHAIN           1..397
FT                   /note="Terminase A protein"
FT                   /id="PRO_0000165275"
FT   REGION          42..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          304..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          356..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..397
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   397 AA;  45280 MW;  247B64DE3EE2D550 CRC64;
     MTWDDHKKNF ARLARDGGYT IAQYAAEFNL NPNTARRYLR AFKEDTRTTD SRKPNKPVRK
     PLKSMIIDHS NDQHAGDHIA AEIAEKERVN AVVSAAVENA KRQNKRINDR SDDHDVITRA
     HRTLRDRLER DTLDDDGERF EFEVGDYLID NVEARKAARA MLRRSGADVL ETTLLEKSLS
     HLLMLENARD TCIRLVQEMR DQQKDDDEGT PPEYRIASML NSCSAQISSL INTIYSIRNN
     YRKESREAEK HALSMGQAGI VKLAYERKRE NNWSVLEAAE FIEAHGGKVP PLMLEQIKAD
     LRAPKTNTDD EENQTASGAP SLEDLDKIAR ERAASRRADA ALWIEHRREE IADIVDTGGY
     GDVDAEGISN EAWLEQDLDE DEEEDEEVTR KLYGDDD