ID   PACC_COLGL              Reviewed;          65 AA.
AC   Q8J254;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=pH-response transcription factor pacC/RIM101;
DE   Flags: Fragment;
GN   Name=pac1;
OS   Colletotrichum gloeosporioides (Anthracnose fungus) (Glomerella cingulata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum gloeosporioides species complex.
OX   NCBI_TaxID=474922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND INDUCTION.
RC   STRAIN=CG-14;
RX   PubMed=12788724; DOI=10.1128/aem.69.6.3258-3262.2003;
RA   Drori N., Kramer-Haimovich H., Rollins J.A., Dinoor A., Okon Y., Pines O.,
RA   Prusky D.;
RT   "External pH and nitrogen source affect secretion of pectate lyase by
RT   Colletotrichum gloeosporioides.";
RL   Appl. Environ. Microbiol. 69:3258-3262(2003).
CC   -!- FUNCTION: Transcription factor that mediates regulation of both
CC       acid- and alkaline-expressed genes in response to ambient pH. At
CC       alkaline ambient pH, activates transcription of alkaline-expressed
CC       genes (including pac1 itself) and represses transcription of acid-
CC       expressed genes (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- INDUCTION: By alkaline conditions. {ECO:0000269|PubMed:12788724}.
CC   -!- SIMILARITY: Belongs to the pacC/RIM101 family. {ECO:0000305}.
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DR   EMBL; AF539700; AAN16381.1; -; mRNA.
DR   AlphaFoldDB; Q8J254; -.
DR   SMR; Q8J254; -.
DR   BRENDA; 4.2.2.2; 1569.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Metal-binding; Nucleus; Repeat; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           <1..>65
FT                   /note="pH-response transcription factor pacC/RIM101"
FT                   /id="PRO_0000046828"
FT   ZN_FING         16..40
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         46..>65
FT                   /note="C2H2-type 2; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   NON_TER         1
FT   NON_TER         65
SQ   SEQUENCE   65 AA;  7635 MW;  49BBB2F5FF230C26 CRC64;
     VCERHVGRKS TNNLNLTCQW NSCRTTTVKR DHITSHIRVH VPLKPHKCEF CGKSFKRPQD
     LKKHV