ID   PACC_PENEC              Reviewed;          70 AA.
AC   Q8J256;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=pH-response transcription factor pacC/RIM101;
DE   Flags: Fragment;
GN   Name=PACC;
OS   Penicillium echinulatum (Mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=60174;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Pocas-Fonseca M.J., Neves E.O., Rocha B.B., Azevedo M.O., Kubicek C.P.;
RT   "Penicillium echinulatum putative transcription factor PacC (pacC gene).";
RL   Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcription factor that mediates regulation of both
CC       acid- and alkaline-expressed genes in response to ambient pH. At
CC       alkaline ambient pH, activates transcription of alkaline-expressed
CC       genes (including pacC itself) and represses transcription of acid-
CC       expressed genes (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the pacC/RIM101 family. {ECO:0000305}.
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DR   EMBL; AF536982; AAN06813.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8J256; -.
DR   SMR; Q8J256; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Metal-binding; Nucleus; Repeat; Repressor;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           <1..>70
FT                   /note="pH-response transcription factor pacC/RIM101"
FT                   /id="PRO_0000046841"
FT   ZN_FING         18..42
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         48..70
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   NON_TER         1
FT   NON_TER         70
SQ   SEQUENCE   70 AA;  8174 MW;  52655E4E1D931596 CRC64;
     EHVCERHVGR KSTHNLNLTC QWGSCNTTTV KRDHITSHLR VHVPLKPHKC DFCGKAFKRP
     QDLKKHVKNH