PACRL_MOUSE
ID PACRL_MOUSE Reviewed; 248 AA.
AC Q9D3X5;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=PACRG-like protein;
GN Name=Pacrgl;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Olfactory bulb, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK016966; BAB30527.1; -; mRNA.
DR EMBL; AK032498; BAC27898.1; -; mRNA.
DR EMBL; BC018481; AAH18481.1; -; mRNA.
DR CCDS; CCDS19281.1; -.
DR RefSeq; NP_080031.1; NM_025755.3.
DR AlphaFoldDB; Q9D3X5; -.
DR SMR; Q9D3X5; -.
DR STRING; 10090.ENSMUSP00000030968; -.
DR iPTMnet; Q9D3X5; -.
DR PhosphoSitePlus; Q9D3X5; -.
DR PaxDb; Q9D3X5; -.
DR PeptideAtlas; Q9D3X5; -.
DR PRIDE; Q9D3X5; -.
DR ProteomicsDB; 294100; -.
DR Antibodypedia; 43692; 58 antibodies from 12 providers.
DR DNASU; 66768; -.
DR Ensembl; ENSMUST00000030968; ENSMUSP00000030968; ENSMUSG00000029089.
DR Ensembl; ENSMUST00000196950; ENSMUSP00000143072; ENSMUSG00000029089.
DR GeneID; 66768; -.
DR KEGG; mmu:66768; -.
DR UCSC; uc008xjs.1; mouse.
DR CTD; 133015; -.
DR MGI; MGI:1914018; Pacrgl.
DR VEuPathDB; HostDB:ENSMUSG00000029089; -.
DR eggNOG; KOG3961; Eukaryota.
DR GeneTree; ENSGT00940000159756; -.
DR InParanoid; Q9D3X5; -.
DR OMA; HKLQWEC; -.
DR OrthoDB; 1327344at2759; -.
DR PhylomeDB; Q9D3X5; -.
DR TreeFam; TF321123; -.
DR BioGRID-ORCS; 66768; 4 hits in 72 CRISPR screens.
DR ChiTaRS; Pacrgl; mouse.
DR PRO; PR:Q9D3X5; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q9D3X5; protein.
DR Bgee; ENSMUSG00000029089; Expressed in animal zygote and 218 other tissues.
DR ExpressionAtlas; Q9D3X5; baseline and differential.
DR Genevisible; Q9D3X5; MM.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR019399; Parkin_co-regulated_protein.
DR PANTHER; PTHR21207; PTHR21207; 1.
DR Pfam; PF10274; ParcG; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 1: Evidence at protein level;
KW Acetylation; Phosphoprotein; Reference proteome.
FT CHAIN 1..248
FT /note="PACRG-like protein"
FT /id="PRO_0000278244"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:Q8N7B6"
FT MOD_RES 47
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
SQ SEQUENCE 248 AA; 27290 MW; B255BBCE0AABCAC9 CRC64;
MQRSECSGGV QLRNRATGSN DQRTSSSTQM KHRTTVQRSK SSSLTSSPEA ARRARPRPSD
KLNPKTINPF GEQPRAPTAF AAIYSQGGIP CRLVHGSVKH RLQWECPPEI LPFDPLLITL
AEGLRETKHP YTFVSKEGFR ELLLVKGAPE KAIPLLPRLI PVLKAALVHS DDEVFERGLS
ALVQLSVVVG PSLNGHLKLL LTSLSKRLMD KKFKEPITSA LQKLEQHGGN ASLIIIKSKI
PTYCSICC
