ASL1_SCHPO
ID ASL1_SCHPO Reviewed; 530 AA.
AC Q09788;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=Alkali-sensitive linkage protein 1;
DE Flags: Precursor;
GN Name=asl1; ORFNames=SPAC13G6.10c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX PubMed=17230583; DOI=10.1002/yea.1443;
RA de Groot P.W.J., Yin Q.Y., Weig M., Sosinska G.J., Klis F.M.,
RA de Koster C.G.;
RT "Mass spectrometric identification of covalently bound cell wall proteins
RT from the fission yeast Schizosaccharomyces pombe.";
RL Yeast 24:267-278(2007).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000269|PubMed:16823372}. Golgi apparatus
CC {ECO:0000269|PubMed:16823372}. Secreted, cell wall
CC {ECO:0000269|PubMed:17230583}. Note=Covalently attached to the cell
CC wall. {ECO:0000269|PubMed:17230583}.
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DR EMBL; CU329670; CAA91103.1; -; Genomic_DNA.
DR PIR; S62439; S62439.
DR RefSeq; NP_592836.1; NM_001018237.2.
DR AlphaFoldDB; Q09788; -.
DR SMR; Q09788; -.
DR BioGRID; 279339; 67.
DR STRING; 4896.SPAC13G6.10c.1; -.
DR CAZy; GH128; Glycoside Hydrolase Family 128.
DR MaxQB; Q09788; -.
DR PaxDb; Q09788; -.
DR EnsemblFungi; SPAC13G6.10c.1; SPAC13G6.10c.1:pep; SPAC13G6.10c.
DR GeneID; 2542895; -.
DR KEGG; spo:SPAC13G6.10c; -.
DR PomBase; SPAC13G6.10c; asl1.
DR VEuPathDB; FungiDB:SPAC13G6.10c; -.
DR eggNOG; ENOG502RXK9; Eukaryota.
DR HOGENOM; CLU_605752_0_0_1; -.
DR InParanoid; Q09788; -.
DR OMA; WGYNWDS; -.
DR PRO; PR:Q09788; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0010339; C:external side of cell wall; NAS:PomBase.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0009277; C:fungal-type cell wall; IDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; ISM:PomBase.
DR GO; GO:0071966; P:fungal-type cell wall polysaccharide metabolic process; IMP:PomBase.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR024655; Unchr_glyco_hydro_catalytic.
DR Pfam; PF11790; Glyco_hydro_cc; 1.
DR SUPFAM; SSF51445; SSF51445; 1.
PE 1: Evidence at protein level;
KW Cell wall; Endoplasmic reticulum; Glycoprotein; Golgi apparatus;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..530
FT /note="Alkali-sensitive linkage protein 1"
FT /id="PRO_0000014190"
FT REGION 69..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 55
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 120
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 128
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 530 AA; 54211 MW; 1C6A0261F63DFF02 CRC64;
MRTTFATVAL AFLSTVGALP YAPNHRHHRR DDDGVLTVYE TILETVYVTA VPGANSSSSY
TSYSTGLASV TESSDDGAST ALPTTSTESV VVTTSAPAAS SSATSYPATF VSTPLYTMDN
VTAPVWSNTS VPVSTPETSA TSSSEFFTSY PATSSESSSS YPASSTEVAS SYSASSTEVT
SSYPASSEVA TSTSSYVAPV SSSVASSSEI SAGSATSYVP TSSSSIALSS VVASASVSAA
NKGVSTPAVS SAAASSSAVV SSVVSSATSV AASSTISSAT SSSASASPTS SSVSGKRGLA
WIPGTDLGYS DNFVNKGINW YYNWGSYSSG LSSSFEYVLN QHDANSLSSA SSVFTGGATV
IGFNEPDLSA AGNPIDAATA ASYYLQYLTP LRESGAIGYL GSPAISNVGE DWLSEFMSAC
SDCKIDFIAC HWYGIDFSNL QDYINSLANY GLPIWLTEFA CTNWDDSNLP SLDEVKTLMT
SALGFLDGHG SVERYSWFAP ATELGAGVGN NNALISSSGG LSEVGEIYIS
