PAFB_MYCTO
ID PAFB_MYCTO Reviewed; 332 AA.
AC P9WIM0; A0A112; L0TA73; P64941; Q10705;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Protein PafB;
DE AltName: Full=Proteasome accessory factor B;
GN Name=pafB; OrderedLocusNames=MT2157;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Part of the pafABC operon, however PafB does not seem to be
CC involved in pupylation or substrate degradation. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with PafC; with which it probably forms a
CC heterocomplex. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PafB family. {ECO:0000305}.
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DR EMBL; AE000516; AAK46438.1; -; Genomic_DNA.
DR PIR; C70768; C70768.
DR RefSeq; WP_003410775.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WIM0; -.
DR SMR; P9WIM0; -.
DR EnsemblBacteria; AAK46438; AAK46438; MT2157.
DR KEGG; mtc:MT2157; -.
DR PATRIC; fig|83331.31.peg.2326; -.
DR HOGENOM; CLU_041141_3_1_11; -.
DR Proteomes; UP000001020; Chromosome.
DR InterPro; IPR026881; WYL_dom.
DR Pfam; PF13280; WYL; 1.
PE 3: Inferred from homology;
FT CHAIN 1..332
FT /note="Protein PafB"
FT /id="PRO_0000427982"
SQ SEQUENCE 332 AA; 35300 MW; 5867925C8A29214E CRC64;
MATSKVERLV NLVIALLSTR GYITAEKIRS SVAGYSDSPS VEAFSRMFER DKNELRDLGI
PLEVGRVSAL EPTEGYRINR DAYALSPVEL TPDEAAAVAV ATQLWESPEL ITATQGALLK
LRAAGVDVDP LDTGAPVAIA SAAAVSGLRG SEDVLGILLS AIDSGQVVQF SHRSSRAEPY
TVRTVEPWGV VTEKGRWYLV GHDRDRDATR VFRLSRIGAQ VTPIGPAGAT TVPAGVDLRS
IVAQKVTEVP TGEQATVWVA EGRATALRRA GRSAGPRQLG GRDGEVIELE IRSSDRLARE
ITGYGADAIV LQPGSLRDDV LARLRAQAGA LA