ID   PAFC_MYCLE              Reviewed;         324 AA.
AC   P54075; Q9ZBD9;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 2.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Protein PafC;
GN   Name=pafC; OrderedLocusNames=ML1330; ORFNames=B2126_C2_220, MLCB2533.26;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- FUNCTION: Does not seem to be involved in pupylation or substrate
CC       degradation. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PafB; with which it probably forms a
CC       heterocomplex. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PafC family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA17199.1; Type=Frameshift; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00017; AAA17199.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AL035310; CAA22940.1; -; Genomic_DNA.
DR   EMBL; AL583921; CAC31711.1; -; Genomic_DNA.
DR   PIR; D87075; D87075.
DR   PIR; S72859; S72859.
DR   RefSeq; NP_301954.1; NC_002677.1.
DR   RefSeq; WP_010908275.1; NC_002677.1.
DR   AlphaFoldDB; P54075; -.
DR   SMR; P54075; -.
DR   STRING; 272631.ML1330; -.
DR   EnsemblBacteria; CAC31711; CAC31711; CAC31711.
DR   KEGG; mle:ML1330; -.
DR   PATRIC; fig|272631.5.peg.2450; -.
DR   Leproma; ML1330; -.
DR   eggNOG; COG2378; Bacteria.
DR   HOGENOM; CLU_041141_2_0_11; -.
DR   OMA; LPMCGTS; -.
DR   Proteomes; UP000000806; Chromosome.
DR   InterPro; IPR028349; PafC.
DR   InterPro; IPR043839; PafC_HTH.
DR   InterPro; IPR026881; WYL_dom.
DR   Pfam; PF19187; HTH_PafC; 1.
DR   Pfam; PF13280; WYL; 1.
DR   PIRSF; PIRSF016838; PafC; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..324
FT                   /note="Protein PafC"
FT                   /id="PRO_0000014123"
FT   CONFLICT        156
FT                   /note="D -> N (in Ref. 1; AAA17199)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   324 AA;  35259 MW;  BA04AE9F324AF846 CRC64;
     MTQLSTRLVR LLNMVPYFQA NPRITRAEAA ADLGVSAKQL DQDFNQLWVC GLPGYGPGDL
     IDFEFSGDTI EVTFSAGIDR PLQLTSPEAI GLLVALRALA NIPGVVDPEA VRSAIAKIEA
     AAVVMGNEAT GSVASVDTRP FSESHAVAAV RAAVRDKQAL VIDYYSASHD TLTSRIVDPI
     RVLLVGDHSY LEAWSREAEG VRLFRFDRIV VARELDEPAA APETVRKALP DTSFFDDDPL
     LPSATLWVAR SVSWIFEYYP MRQAHELPDG SFQAVMTYAS DAWMTRLVLG FGSAVQVQAP
     EALAYRVRNA AVAALESYQV TAQA