ID   PAG62_BUBBU             Reviewed;          15 AA.
AC   P86371; P85050; P86376; P86377;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-NOV-2009, sequence version 1.
DT   03-AUG-2022, entry version 12.
DE   RecName: Full=Pregnancy-associated glycoprotein 62;
DE            Short=PAG 62;
DE            EC=3.4.23.- {ECO:0000250|UniProtKB:P85050};
DE   AltName: Full=Pregnancy-associated glycoprotein 58F;
DE   AltName: Full=Pregnancy-associated glycoprotein 65E;
DE   AltName: Full=Pregnancy-associated glycoprotein 73I {ECO:0000303|PubMed:23634647};
DE   Flags: Fragment;
OS   Bubalus bubalis (Domestic water buffalo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bubalus.
OX   NCBI_TaxID=89462;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC   TISSUE=Fetal cotyledon {ECO:0000269|PubMed:23634647};
RX   PubMed=23634647; DOI=10.1186/1746-6148-9-89;
RA   Barbato O., Melo de Sousa N., Barile V.L., Canali C., Beckers J.F.;
RT   "Purification of pregnancy-associated glycoproteins from late-pregnancy
RT   Bubalus bubalis placentas and development of a radioimmunoassay for
RT   pregnancy diagnosis in water buffalo females.";
RL   BMC Vet. Res. 9:89-89(2013).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-13, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND
RP   DEVELOPMENTAL STAGE.
RC   TISSUE=Trophectoderm;
RX   PubMed=18308351; DOI=10.1016/j.rvsc.2008.01.004;
RA   Barbato O., Sousa N.M., Klisch K., Clerget E., Debenedetti A., Barile V.L.,
RA   Malfatti A., Beckers J.F.;
RT   "Isolation of new pregnancy-associated glycoproteins from water buffalo
RT   (Bubalus bubalis) placenta by Vicia villosa affinity chromatography.";
RL   Res. Vet. Sci. 85:457-466(2008).
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space
CC       {ECO:0000269|PubMed:18308351}.
CC   -!- TISSUE SPECIFICITY: Expressed in chorionic epithelium (trophectoderm).
CC       {ECO:0000269|PubMed:18308351, ECO:0000269|PubMed:23634647}.
CC   -!- DEVELOPMENTAL STAGE: Expressed during 5th month of pregnancy and
CC       continues through the gestation period. {ECO:0000269|PubMed:18308351,
CC       ECO:0000269|PubMed:23634647}.
CC   -!- PTM: N-glycosylated. {ECO:0000250|UniProtKB:P85048}.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family. {ECO:0000255}.
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DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Aspartyl protease; Direct protein sequencing; Glycoprotein; Hydrolase;
KW   Protease; Secreted.
FT   CHAIN           1..>15
FT                   /note="Pregnancy-associated glycoprotein 62"
FT                   /id="PRO_0000389543"
FT   NON_TER         15
FT                   /evidence="ECO:0000303|PubMed:23634647"
SQ   SEQUENCE   15 AA;  1690 MW;  5D9DEA672A8FEBFD CRC64;
     RGSXLTHLPL RNISD