ID   PAG74_BISBI             Reviewed;          25 AA.
AC   P84917;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 30.
DE   RecName: Full=Pregnancy-associated glycoprotein 74;
DE            EC=3.4.23.-;
DE   AltName: Full=AmbPAG 74 kDa;
DE   Flags: Fragment;
OS   Bison bison (American bison) (Bos bison).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bison.
OX   NCBI_TaxID=9901;
RN   [1]
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND
RP   GLYCOSYLATION.
RC   TISSUE=Placenta;
RX   PubMed=17543308; DOI=10.1016/j.ygcen.2007.04.011;
RA   Kiewisz J., Melo de Sousa N., Beckers J.-F.M.P., Vervaecke H.,
RA   Panasiewicz G., Szafranska B.;
RT   "Isolation of pregnancy-associated glycoproteins from placenta of the
RT   American bison (Bison bison) at first half of pregnancy.";
RL   Gen. Comp. Endocrinol. 155:164-175(2008).
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC   -!- TISSUE SPECIFICITY: Placental cotyledons.
CC       {ECO:0000269|PubMed:17543308}.
CC   -!- DEVELOPMENTAL STAGE: Expressed between month 3 and month 4 of
CC       pregnancy. {ECO:0000269|PubMed:17543308}.
CC   -!- PTM: N-glycosylated. {ECO:0000269|PubMed:17543308}.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family. {ECO:0000255}.
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DR   AlphaFoldDB; P84917; -.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Aspartyl protease; Direct protein sequencing; Glycoprotein; Hydrolase;
KW   Protease; Secreted.
FT   CHAIN           1..>25
FT                   /note="Pregnancy-associated glycoprotein 74"
FT                   /id="PRO_0000249181"
FT   CARBOHYD        4
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        21
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         25
SQ   SEQUENCE   25 AA;  2840 MW;  02B534831DEF26CA CRC64;
     RGSNLTIHPL RNIRDIFYVG NITIG