ID   PAG75_BUBBU             Reviewed;          20 AA.
AC   P85048; P86369; P86372; P86375; P86378; P86379;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 24.
DE   RecName: Full=Pregnancy-associated glycoprotein 75;
DE            Short=PAG 75;
DE            EC=3.4.23.-;
DE   AltName: Full=Pregnancy-associated glycoprotein 60K;
DE   AltName: Full=Pregnancy-associated glycoprotein 63H;
DE   AltName: Full=Pregnancy-associated glycoprotein 69A;
DE   AltName: Full=Pregnancy-associated glycoprotein 76D;
DE   AltName: Full=Pregnancy-associated glycoprotein 76G;
DE   Flags: Fragment;
OS   Bubalus bubalis (Domestic water buffalo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bubalus.
OX   NCBI_TaxID=89462;
RN   [1]
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND
RP   DEVELOPMENTAL STAGE.
RC   TISSUE=Trophectoderm;
RX   PubMed=18308351; DOI=10.1016/j.rvsc.2008.01.004;
RA   Barbato O., Sousa N.M., Klisch K., Clerget E., Debenedetti A., Barile V.L.,
RA   Malfatti A., Beckers J.F.;
RT   "Isolation of new pregnancy-associated glycoproteins from water buffalo
RT   (Bubalus bubalis) placenta by Vicia villosa affinity chromatography.";
RL   Res. Vet. Sci. 85:457-466(2008).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-10, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC   TISSUE=Fetal cotyledon;
RX   PubMed=23634647; DOI=10.1186/1746-6148-9-89;
RA   Barbato O., Melo de Sousa N., Barile V.L., Canali C., Beckers J.F.;
RT   "Purification of pregnancy-associated glycoproteins from late-pregnancy
RT   Bubalus bubalis placentas and development of a radioimmunoassay for
RT   pregnancy diagnosis in water buffalo females.";
RL   BMC Vet. Res. 9:89-89(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18308351}.
CC   -!- TISSUE SPECIFICITY: Expressed in chorionic epithelium (trophectoderm).
CC       {ECO:0000269|PubMed:18308351, ECO:0000269|PubMed:23634647}.
CC   -!- DEVELOPMENTAL STAGE: Expressed during month 5 of pregnancy.
CC       {ECO:0000269|PubMed:18308351, ECO:0000269|PubMed:23634647}.
CC   -!- PTM: N-glycosylated. {ECO:0000250|UniProtKB:P84917}.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family. {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Aspartyl protease; Direct protein sequencing; Glycoprotein; Hydrolase;
KW   Protease; Secreted.
FT   CHAIN           1..>20
FT                   /note="Pregnancy-associated glycoprotein 75"
FT                   /id="PRO_0000271230"
FT   NON_TER         20
SQ   SEQUENCE   20 AA;  2373 MW;  364AEA440F18D95A CRC64;
     RGSXLTIHPL RNIRDFFYVG