PAG76_BISBI
ID PAG76_BISBI Reviewed; 25 AA.
AC P84918;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 30.
DE RecName: Full=Pregnancy-associated glycoprotein 76;
DE EC=3.4.23.-;
DE AltName: Full=AmbPAG 76 kDa;
DE Flags: Fragment;
OS Bison bison (American bison) (Bos bison).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bison.
OX NCBI_TaxID=9901;
RN [1]
RP PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND
RP GLYCOSYLATION.
RC TISSUE=Placenta;
RX PubMed=17543308; DOI=10.1016/j.ygcen.2007.04.011;
RA Kiewisz J., Melo de Sousa N., Beckers J.-F.M.P., Vervaecke H.,
RA Panasiewicz G., Szafranska B.;
RT "Isolation of pregnancy-associated glycoproteins from placenta of the
RT American bison (Bison bison) at first half of pregnancy.";
RL Gen. Comp. Endocrinol. 155:164-175(2008).
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC -!- TISSUE SPECIFICITY: Placental cotyledons.
CC {ECO:0000269|PubMed:17543308}.
CC -!- DEVELOPMENTAL STAGE: Expressed between month 3 and month 4 of
CC pregnancy. {ECO:0000269|PubMed:17543308}.
CC -!- PTM: N-glycosylated. {ECO:0000269|PubMed:17543308}.
CC -!- SIMILARITY: Belongs to the peptidase A1 family. {ECO:0000255}.
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DR AlphaFoldDB; P84918; -.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Aspartyl protease; Direct protein sequencing; Glycoprotein; Hydrolase;
KW Protease; Secreted.
FT CHAIN 1..>25
FT /note="Pregnancy-associated glycoprotein 76"
FT /id="PRO_0000249182"
FT CARBOHYD 4
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 21
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT NON_TER 25
SQ SEQUENCE 25 AA; 2840 MW; 02B534831DEF26CA CRC64;
RGSNLTIHPL RNIRDIFYVG NITIG