ID   PAHO_CHICH              Reviewed;          36 AA.
AC   P41519;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Pancreatic hormone;
DE            Short=PH;
DE   AltName: Full=Pancreatic polypeptide;
DE            Short=PP;
GN   Name=PPY;
OS   Chinchilla chinchilla (Short-tailed chinchilla) (Chinchilla brevicaudata).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha;
OC   Chinchillidae; Chinchilla.
OX   NCBI_TaxID=10152;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Pancreas;
RX   PubMed=2235678; DOI=10.1016/0196-9781(90)90180-d;
RA   Eng J., Kleinman W.A., Chu L.S.;
RT   "Purification of peptide hormones from chinchilla pancreas by chemical
RT   assay.";
RL   Peptides 11:683-685(1990).
CC   -!- FUNCTION: Pancreatic hormone is synthesized in pancreatic islets of
CC       Langerhans and acts as a regulator of pancreatic and gastrointestinal
CC       functions.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR   PIR; B60413; B60413.
DR   AlphaFoldDB; P41519; -.
DR   SMR; P41519; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR015480; Pancreatic_hormone.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   PANTHER; PTHR10533; PTHR10533; 1.
DR   PANTHER; PTHR10533:SF2; PTHR10533:SF2; 1.
DR   Pfam; PF00159; Hormone_3; 1.
DR   PRINTS; PR00278; PANCHORMONE.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Secreted.
FT   PEPTIDE         1..36
FT                   /note="Pancreatic hormone"
FT                   /id="PRO_0000044795"
FT   MOD_RES         36
FT                   /note="Tyrosine amide"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   36 AA;  4215 MW;  761B717670E3308F CRC64;
     APLEPVYPGD NATPEQMAQY AAEMRRYINM LTRPRY