ID   PAHO_DIDVI              Reviewed;          36 AA.
AC   P18107;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Pancreatic hormone;
DE            Short=PH;
DE   AltName: Full=Pancreatic polypeptide;
DE            Short=PP;
GN   Name=PPY;
OS   Didelphis virginiana (North American opossum) (Didelphis marsupialis
OS   virginiana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Didelphimorphia; Didelphidae; Didelphis.
OX   NCBI_TaxID=9267;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Pancreas;
RX   PubMed=2695899; DOI=10.1016/0196-9781(89)90012-0;
RA   Yu J.-H., Eng J., Rattan S., Yalow R.S.;
RT   "Opossum insulin, glucagon and pancreatic polypeptide: amino acid
RT   sequences.";
RL   Peptides 10:1195-1197(1989).
CC   -!- FUNCTION: Pancreatic hormone is synthesized in pancreatic islets of
CC       Langerhans and acts as a regulator of pancreatic and gastrointestinal
CC       functions.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR   PIR; JQ0365; JQ0365.
DR   AlphaFoldDB; P18107; -.
DR   SMR; P18107; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR015480; Pancreatic_hormone.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   PANTHER; PTHR10533; PTHR10533; 1.
DR   PANTHER; PTHR10533:SF2; PTHR10533:SF2; 1.
DR   Pfam; PF00159; Hormone_3; 1.
DR   PRINTS; PR00278; PANCHORMONE.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Secreted.
FT   PEPTIDE         1..36
FT                   /note="Pancreatic hormone"
FT                   /id="PRO_0000044796"
FT   MOD_RES         36
FT                   /note="Tyrosine amide"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   36 AA;  4238 MW;  7611E5B281A6221F CRC64;
     APQEPVYPGD DATPEQMAKY AAELRRYINR LTRPRY