ASMA_ECOLI
ID ASMA_ECOLI Reviewed; 617 AA.
AC P28249; P76390;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Protein AsmA;
DE Flags: Precursor;
GN Name=asmA; Synonyms=yegA; OrderedLocusNames=b2064, JW2049;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-379.
RC STRAIN=K12;
RX PubMed=7476172; DOI=10.1111/j.1365-2958.1995.tb02439.x;
RA Misra R., Miao Y.;
RT "Molecular analysis of asmA, a locus identified as the suppressor of OmpF
RT assembly mutants of Escherichia coli K-12.";
RL Mol. Microbiol. 16:779-788(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-200.
RX PubMed=1324907; DOI=10.1128/jb.174.17.5647-5653.1992;
RA Wang L., Weiss B.;
RT "dcd (dCTP deaminase) gene of Escherichia coli: mapping, cloning,
RT sequencing, and identification as a locus of suppressors of lethal dut
RT (dUTPase) mutations.";
RL J. Bacteriol. 174:5647-5653(1992).
CC -!- FUNCTION: Involved in the inhibition of assembly of mutant ompF
CC proteins. In general, could be involved in the assembly of outer
CC membrane proteins.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the AsmA family. {ECO:0000305}.
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DR EMBL; U11035; AAD14778.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75125.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15917.1; -; Genomic_DNA.
DR EMBL; M90069; AAA23670.1; -; Genomic_DNA.
DR PIR; G64972; G64972.
DR RefSeq; NP_416568.1; NC_000913.3.
DR RefSeq; WP_001252331.1; NZ_STEB01000002.1.
DR AlphaFoldDB; P28249; -.
DR BioGRID; 4259685; 263.
DR DIP; DIP-9175N; -.
DR IntAct; P28249; 9.
DR STRING; 511145.b2064; -.
DR TCDB; 9.B.22.2.1; the leukotoxin secretion morphogenesis protein c (morc) family.
DR jPOST; P28249; -.
DR PaxDb; P28249; -.
DR PRIDE; P28249; -.
DR EnsemblBacteria; AAC75125; AAC75125; b2064.
DR EnsemblBacteria; BAA15917; BAA15917; BAA15917.
DR GeneID; 946582; -.
DR KEGG; ecj:JW2049; -.
DR KEGG; eco:b2064; -.
DR PATRIC; fig|1411691.4.peg.187; -.
DR EchoBASE; EB1336; -.
DR eggNOG; COG2982; Bacteria.
DR HOGENOM; CLU_012870_3_1_6; -.
DR InParanoid; P28249; -.
DR OMA; FPWLGLE; -.
DR PhylomeDB; P28249; -.
DR BioCyc; EcoCyc:EG11361-MON; -.
DR PRO; PR:P28249; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0090313; P:regulation of protein targeting to membrane; IMP:EcoCyc.
DR InterPro; IPR007844; AsmA.
DR Pfam; PF05170; AsmA; 1.
PE 3: Inferred from homology;
KW Periplasm; Reference proteome; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..617
FT /note="Protein AsmA"
FT /id="PRO_0000020759"
FT REGION 302..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 354..379
FT /note="GMNFTDVATQMTNKSGLLEITQLQGK -> NEFYRCCHANDQQVGFAGNYST
FT AGQT (in Ref. 1; AAD14778)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 617 AA; 68963 MW; 23AD060D864BC680 CRC64;
MRRFLTTLMI LLVVLVAGLS ALVLLVNPND FRDYMVKQVA ARSGYQLQLD GPLRWHVWPQ
LSILSGRMSL TAQGASQPLV RADNMRLDVA LLPLLSHQLS VKQVMLKGAV IQLTPQTEAV
RSEDAPVAPR DNTLPDLSDD RGWSFDISSL KVADSVLVFQ HEDDEQVTIR NIRLQMEQDP
QHRGSFEFSG RVNRDQRDLT ISLNGTVDAS DYPHDLTAAI EQINWQLQGA DLPKQGIQGQ
GSFQAQWQES HKRLSFNQIS LTANDSTLSG QAQVTLTEKP EWQLRLQFPQ LNLDNLIPLN
ETANGENGAA QQGQSQSTLP RPVISSRIDE PAYQGLQGFT ADILLQASNV RWRGMNFTDV
ATQMTNKSGL LEITQLQGKL NGGQVSLPGT LDATSINPRI NFQPRLENVE IGTILKAFNY
PISLTGKMSL AGDFSGADID ADAFRHNWQG QAHVEMTDTR MEGMNFQQMI QQAVERNGGD
VKAAENFDNV TRLDRFTTDL TLKDGVVTLN DMQGQSPVLA LTGEGMLNLA DQTCDTQFDI
RVVGGWNGES KLIDFLKETP VPLRVYGNWQ QLNYSLQVDQ LLRKHLQDEA KRRLNDWAER
NKDSRNGKDV KKLLEKM
