ID   PAHO_MACMU              Reviewed;          36 AA.
AC   P33684;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Pancreatic hormone;
DE            Short=PH;
DE   AltName: Full=Pancreatic polypeptide;
DE            Short=PP;
GN   Name=PPY;
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=2003150; DOI=10.1016/0167-0115(91)90005-2;
RA   Yu J.-H., Xin Y., Eng J., Yalow R.S.;
RT   "Rhesus monkey gastroenteropancreatic hormones: relationship to human
RT   sequences.";
RL   Regul. Pept. 32:39-45(1991).
CC   -!- FUNCTION: Pancreatic hormone is synthesized in pancreatic islets of
CC       Langerhans and acts as a regulator of pancreatic and gastrointestinal
CC       functions.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR   PIR; C60071; C60071.
DR   AlphaFoldDB; P33684; -.
DR   SMR; P33684; -.
DR   STRING; 9544.ENSMMUP00000004281; -.
DR   eggNOG; ENOG502TD4B; Eukaryota.
DR   HOGENOM; CLU_165150_1_0_1; -.
DR   InParanoid; P33684; -.
DR   Proteomes; UP000006718; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR   GO; GO:0005179; F:hormone activity; IBA:GO_Central.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IBA:GO_Central.
DR   GO; GO:0031841; F:neuropeptide Y receptor binding; IBA:GO_Central.
DR   GO; GO:0007631; P:feeding behavior; IBA:GO_Central.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IBA:GO_Central.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR015480; Pancreatic_hormone.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   PANTHER; PTHR10533; PTHR10533; 1.
DR   PANTHER; PTHR10533:SF2; PTHR10533:SF2; 1.
DR   Pfam; PF00159; Hormone_3; 1.
DR   PRINTS; PR00278; PANCHORMONE.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Reference proteome;
KW   Secreted.
FT   PEPTIDE         1..36
FT                   /note="Pancreatic hormone"
FT                   /id="PRO_0000044800"
FT   MOD_RES         36
FT                   /note="Tyrosine amide"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   36 AA;  4183 MW;  761B717671A7758F CRC64;
     APLEPVYPGD NATPEQMAQY AADLRRYINM LTRPRY