ID   PAHO_STRCA              Reviewed;          36 AA.
AC   P11967;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Pancreatic hormone;
DE            Short=PH;
DE   AltName: Full=Pancreatic polypeptide;
DE            Short=PP;
GN   Name=PPY;
OS   Struthio camelus (Common ostrich).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=8801;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=3623804; DOI=10.1111/j.1399-3011.1987.tb02307.x;
RA   Litthauer D., Oelofsen W.;
RT   "Purification and primary structure of ostrich pancreatic polypeptide.";
RL   Int. J. Pept. Protein Res. 29:739-745(1987).
CC   -!- FUNCTION: Pancreatic hormone is synthesized in pancreatic islets of
CC       Langerhans and acts as a regulator of pancreatic and gastrointestinal
CC       functions.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A28578; A28578.
DR   AlphaFoldDB; P11967; -.
DR   SMR; P11967; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   PANTHER; PTHR10533; PTHR10533; 1.
DR   Pfam; PF00159; Hormone_3; 1.
DR   PRINTS; PR00278; PANCHORMONE.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Secreted.
FT   PEPTIDE         1..36
FT                   /note="Pancreatic hormone"
FT                   /id="PRO_0000044806"
FT   MOD_RES         36
FT                   /note="Tyrosine amide"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   36 AA;  4209 MW;  679DFFD62494316C CRC64;
     GPAQPTYPGD DAPVEDLVRF YDNLQQYLNV VTRHRY